Korean Prostate Cancer Patients Have Worse Disease Characteristics than their American Counterparts

Kang, Dong Il; Chung, Jae Il; Ha, Hong Koo; Min, Kweon Sik; Yoon, Joong-Han; Kim, Wansuk; Seo, Won Ik; Kang, Pil Moon; Jung, Soo Jin; Kim, Isaac Yi

doi:10.7314/apjcp.2013.14.11.6913

Cited by 31 publications

(28 citation statements)

References 13 publications

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“…Although the Korean studies enrolled fewer patients, the race- and nation-specific characteristics of prostate cancer should be considered to develop a more accurate prediction model. Koreans with prostate cancer in whom a radical prostatectomy is indicated had poorer characteristics than Americans (29). It is important that a more specific prediction model in terms of race and nation be developed.…”

Section: Discussionmentioning

confidence: 99%

Cancer of the Prostate Risk Assessment (CAPRA) Preoperative Score Versus Postoperative Score (CAPRA-S): Ability to Predict Cancer Progression and Decision-Making Regarding Adjuvant Therapy after Radical Prostatectomy

Seo

Kang

et al. 2014

J Korean Med Sci

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The University of California, San Francisco, announced in 2011 Cancer of the Prostate Risk Assessment Postsurgical (CAPRA-S) score which included pathologic data, but there were no results for comparing preoperative predictors with the CAPRA-S score. We evaluated the validation of the CAPRA-S score in our institution and compare the result with the preoperative progression predictor, CAPRA score. Data of 130 patients were reviewed who underwent radical prostatectomy for localized prostate cancer from 2008 to 2013. Performance of CAPRA-S score in predicting progression free probabilities was assessed through Kaplan Meier analysis and Cox proportional hazards regression test. Additionally, prediction probability was compared with preoperative CAPRA score by logistic regression analysis. Comparing CAPRA score, the CAPRA-S score showed improved prediction ability for 5 yr progression free survival (concordance index 0.80, P = 0.04). After risk group stratification, 3 group model of CAPRA-S was superior than 3 group model of CAPRA for 3-yr progression free survival and 5-yr progression free survival (concordance index 0.74 vs. 0.70, 0.77 vs. 0.71, P < 0.001). Finally the CAPRA-S score was the more ideal predictor concerned with adjuvant therapy than the CAPRA score through decision curve analysis. The CPARA-S score is a useful predictor for disease progression after radical prostatectomy.Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Cancer of the Prostate Risk Assessment (CAPRA) Preoperative Score Versus Postoperative Score (CAPRA-S): Ability to Predict Cancer Progression and Decision-Making Regarding Adjuvant Therapy after Radical Prostatectomy

Seo

Kang

et al. 2014

J Korean Med Sci

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“…This is the paradox of prostatic cancer: autopsy examination of men aged 70-79 reveals prostate cancer in 39% and this increases to 43% in those aged 80. Kang et al, reported that American have less severe characteristics than Korean prostate cancer patients (Kang et al, 2013). Increased incidence, disease burden and fatality make the cancer a global health problem.…”

Section: Epidemiologymentioning

confidence: 99%

“…In Asia, incidence of prostate cancer and mortality rate has increased (Moore et al, 2010). Study shows that Korean people have worse disease than American people (Kang et al, 2013). Initial treatment of prostate cancer is androgen deprivation (Zhi et al, 2014).…”

Section: Epidemiologymentioning

confidence: 99%

Epidemiology, Etiology, Diagnosis and Treatment of Prostate Cancer

Daniyal¹,

Siddiqui²,

Akram³

et al. 2014

Asian Pacific Journal of Cancer Prevention

155

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Prostate cancer is more common in men over the age of 65 years. There are 15% cases with positive family history of prostate cancer Worldwide. Prostate cancer is the second leading cause of death among the U.S. men. Prostate cancer incidence is strongly related to age with the highest rates in older man. Globally millions of people are suffering from this disease. This study aims to provide awareness about prostate cancer as well as an updated knowledge about the epidemiology, etiology, diagnosis and treatment of prostate cancer.

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“…7,9,10 However, the new 5-tiered grading system has not been validated in Asian prostate cancer patients. Because prostate cancer in Asians is reported to have more aggressive pathological characteristics 11 and worse oncological outcomes than that in Western patients, [12][13][14][15] the prognostic value of the new system in Asian prostate cancer patients needs to be validated before its clinical application. Therefore, we aimed to evaluate the prognostic value of the new 5-tiered grading system, with respect to both biopsy and pathologic grade, in Korean patients with prostate cancer who underwent radical prostatectomy.…”

Section: Introductionmentioning

confidence: 99%

Value of the New 5-Tiered Prostate Cancer Grade Group System on Predicting Oncological Outcomes for Radical Prostatectomy Population in Korea

Cho

Yoo

Park

et al. 2018

Korean J Urol Oncol

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Purpose: We evaluated the prognostic value of the 5-tiered grade group in Korean patients who underwent radical prostatectomy. Materials and Methods: Between 1996 and 2016, a number of 2,883 consecutive patients who underwent radical prostatectomy were included for the analysis. The impacts of biopsy and pathologic grade group on predicting biochemical recurrence (BCR) were assessed using multivariate analysis. Median follow-up duration was 49.0 months. Results: Mean age was 66.5 years and prostate-specific antigen (PSA) was 11.8 ng/mL. Prostate cancer was locally advanced on magnetic resonance imaging in 13.4%. Biopsy grade group was as follows: 1 (46.8%), 2 (19.8%), 3 (14.2%), 4 (14.1%), and 5 (5.1%). Pathology stage was ≤T2 in 63.6%, T3a in 26.0%, and T3b/T4 in 10.4% patients.

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Korean Prostate Cancer Patients Have Worse Disease Characteristics than their American Counterparts

Cited by 31 publications

References 13 publications

Cancer of the Prostate Risk Assessment (CAPRA) Preoperative Score Versus Postoperative Score (CAPRA-S): Ability to Predict Cancer Progression and Decision-Making Regarding Adjuvant Therapy after Radical Prostatectomy

Cancer of the Prostate Risk Assessment (CAPRA) Preoperative Score Versus Postoperative Score (CAPRA-S): Ability to Predict Cancer Progression and Decision-Making Regarding Adjuvant Therapy after Radical Prostatectomy

Epidemiology, Etiology, Diagnosis and Treatment of Prostate Cancer

Value of the New 5-Tiered Prostate Cancer Grade Group System on Predicting Oncological Outcomes for Radical Prostatectomy Population in Korea

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