Kontseptsiya allostaza i adaptatsiiya cheloveka na Severe

Кривощеков, С. Г.; Кривощёков, С Г; Belisheva, N. K.; Nikolaeva, Elena; Vergunov, Eugeny; Мартынова, А. А.; Elnikova, Oksana; Prjanichnikov, S V; Пряничников, С В; Anufriev, G.N.; Балиоз, Н. В.

doi:10.33396/1728-0869-2016-7-17-25

Cited by 11 publications

(4 citation statements)

References 10 publications

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“…The individual's reaction to what they consider to be extremely severe environmental situations over an extended period of time triggers these reactions. It derives from allostasis, the idea that an organism can achieve stability through change, and the premise that a healthy body requires regular modifications to its internal physiological environment [37,38]. Allostatic load is a term used to describe the cumulative effect of daily experiences, including subtle and long standing life events as well as major challenges, on a person's physiology, including but not limited to poor sleep and circadian disruption, lack of exercise, smoking, alcohol consumption, and an unhealthy diet [39].…”

Section: Stress and Allostatic Loadmentioning

confidence: 99%

Interaction of Allostatic Load With Immune, Inflammatory, and Coagulation Systems

Hassanpour

2023

Immunoregulation

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Dysregulation of the immune system, as well as the endocrine, metabolic, and coagulation systems, has been linked to stress. The type of stressor (acute or chronic) may have a differential effect on immune function, with brief acute stress enhancing some parameters of immunity and chronic stress having a negative effect on many parameters of immune function. The hypothalamic-pituitary-adrenal axis and autonomic (sympathetic and parasympathetic) nervous systems mediate stress and immune functions. Exposure to frequent stressors can lead to repeated physiological arousal, failure to adapt to repeated stressors, failure to terminate the stress response after the stressor has ceased, and inadequate allostatic load to the stressor. The allostatic load provides an overall and body system-specific mechanistic relationship between stressor exposures and health outcomes that may explain minority health disparities. Multiple physiological systems interact at differing levels of activity in this condition. Principally, the severity of allostatic load is determined by using biomarkers of numerous body systems that depict physiological disturbances. There is a substantial connection between stress, immune function, inflammation, and coagulation. Consequently, immune/inflammatory/coagulation biomarkers may play crucial roles in the calculation of allostatic load, and the recommendation of additional biomarkers may improve the estimation accuracy of allostatic load.

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Section: Stress and Allostatic Loadmentioning

confidence: 99%

Interaction of Allostatic Load With Immune, Inflammatory, and Coagulation Systems

Hassanpour

2023

Immunoregulation

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“…Cold exposure, e.g., under climatic conditions of the North, has a significant impact on human health; it modifies clinical parameters in healthy people [1] and constitutes a risk factor for the development of various pathologies [2]. This is especially true for residents of temperate climatic zones moving to the North for various reasons: they adapt to cold by any of the possible mechanisms suitable for particular individuals [3,4].…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular system parameters in participants of Arctic expeditions

Nb¹,

Алчинова²,

Cherepov³

et al. 2020

Int J Occup Med Environ Health

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Objectives: A method of continuous heart rate (HR) and blood pressure (BP) recording was used for the evaluation of the cardiovascular system parameters in participants of short-term (<1 month) high-latitude expeditions, in comparison with the parameters of residents of Central Russia and the Arctic region. Material and Methods: A dynamic examination of participants of Arctic expeditions (30 men, residents of middle-latitude regions, aged 46.7±1.7 years), workers permanently living in Central Russia (the Moscow region, 44 men, aged 46.7±1.0 years) and residents of the North (the Murmansk region, 35 men, aged 46.6±1.3 years) was performed. The authors used a spiroartheriocardiorythmograph allowing the parallel recording of HR, BP, spectral characteristics of HR variability (HRV) and the variability of systolic BP (sBP) and diastolic BP (dBP), cardiac performance parameters, and spontaneous baroreflex sensitivity (BRS). The parameters were recorded at rest, in a sitting position, over 2 min. Results: The basic clinical parameters (HR, BP and cardiac performance) did not differ in the workers living in different climatic zones. However, the residents of the North demonstrated a lower total power (TP) of the dBP variability spectrum and a lower relative power of the high-frequency (HF) range in both the sBP and dBP variability spectra. The participants of expeditions to the North had a lower TP of the HRV spectrum (in comparison with both control groups) that did not change during the expeditions; BRS was reduced, while the TP of the sBP spectrum was increased in comparison with the corresponding parameters obtained from the residents of circumpolar regions, and decreased during the expedition in parallel with a decrease in the sBP values. The TP of both the sBP and dBP variability spectra, as well as the power of the HF range in these spectra, were similar in the participants of expeditions to those obtained from the residents of Central Russia, and they considerably surpassed the corresponding parameters in the northerners surveyed. Conclusions: The revealed peculiarities of the cardiovascular system in the participants of high-latitude expeditions can be considered as correlates of positive, and adequate in terms of the physiological value, adaptive shifts in the autonomous regulation of the cardiovascular system.

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“…Activation of the SNS attests to the degree of the allostatic load in the trial subject and corresponds to the stress level of the regulatory systems [5,6]. Activation of the parasympathetic nervous system, which originated earlier in evolution than the sympathetic system to provide stability within the internal environment, demonstrates the level of the body's reserve possibilities.…”

Section: Introductionmentioning

confidence: 99%

How hardiness and the quality of life relate to the parameters of autonomic balance

Nikolaeva

Elnikova²,

Vergunov

et al. 2018

SHS Web Conf.

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The purpose of the research was to evaluate the prognostic significance of the two tests most often used by psychologists for describing of the subject's quality of life: the Short Form-36 Health Status Survey (SF-36) and the Hardiness Test (Maddi, 1998). As an indicator of the state of internal control, the activity of the sympathetic nervous system (SNS) and the parasympathetic nervous system (PSNS) was chosen. Our study sample consisted of 59 students and office workers (mean age of 25.1 ± 11.0 years). The study was conducted in two successive stages. During each of the stages, the heart rate was recorded, the slow and the fast waves on the cardiogram were assessed. During the first stage, the R-R intervals were recorded with the subject in a state of quiet wakefulness; during the second, while the subject's health was being discussed. A second recording was done for further elaboration (once again while the test subject was in the process of describing the state of their health). The only correlation between a person's own description and the actual inner state arises when they are describing their real responsibilities and how they carry them out.

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Kontseptsiya allostaza i adaptatsiiya cheloveka na Severe

Cited by 11 publications

References 10 publications

Interaction of Allostatic Load With Immune, Inflammatory, and Coagulation Systems

Interaction of Allostatic Load With Immune, Inflammatory, and Coagulation Systems

Cardiovascular system parameters in participants of Arctic expeditions

How hardiness and the quality of life relate to the parameters of autonomic balance

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