Konjac glucomannan-based hydrogels with health-promoting effects for potential edible electronics applications: A mini-review

Waresindo, William Xaveriano; Priyanto, Aan; Sihombing, Yuan Alfinsyah; Hapidin, Dian Ahmad; Edikresnha, Dhewa; Aimon, Akfiny Hasdi; Suciati, Tri; Khairurrijal, Khairurrijal

doi:10.1016/j.ijbiomac.2023.125888

Cited by 9 publications

(2 citation statements)

References 86 publications

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“…In other field, such as in agriculture, hydrogel can be used as an effective water storage in agriculture, offering a suitable means for both water retention and controlled release [3]. Also, hydrogel can be applied as the soil amendment, hygienic napkins [14], disposable diapers [8], sealing, coal dewatering, artificial snow, food additives [15], the construction industry, responsive materials, wastewater treatment [1], dye adsorption [7], and potential edible electronics applications [16]. Das et al manufactured superabsorbent hydrogels (SAH) based on carboxymethylcellulose sodium salt (CMCNa) and hydroxyethylcellulose (HEC) for agricultural applications, utilizing citric acid (CA) as a crosslinker.…”

Section: Introductionmentioning

confidence: 99%

Enhanced Superabsorbency of Cellulose-Based Hydrogels in NaOH Solution: Synthesis, Characterization, and Performance Evaluation

Nafisah,

Rodhiyah,

Luthfianti

et al. 2024

J. Phys.: Conf. Ser.

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Cellulose is a natural polymer that is abundantly available in nature. This study successfully developed cellulose dissolved in NaOH and formed into hydrogels using the freeze-thaw method. NaOH solution concentration as a cellulose solvent varied from 1% (CN1) to 5% (CN5) by weight. Six cycles of freezing and thawing were performed for 20 hours at -23°C and 4 hours at 37°C. Subsequently, morphological analysis, swelling degree, weight loss, and compression testing were conducted to assess the physical properties of cellulose-based hydrogels. The results demonstrate that as the concentration of NaOH increases, the resulting hydrogel exhibits smaller pore sizes, as evidenced by optical microscope images. Additionally, the swelling degree increased with the increasing NaOH fraction. The swelling tests were performed in both distilled water and PBS solutions. Notably, soaking the hydrogels in PBS solution demonstrated their potential as superabsorbent hydrogels (SAH). Furthermore, increased NaOH fraction was associated with higher weight loss, greater Young’s modulus, and reduced compressive strength.

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Section: Introductionmentioning

confidence: 99%

Enhanced Superabsorbency of Cellulose-Based Hydrogels in NaOH Solution: Synthesis, Characterization, and Performance Evaluation

Nafisah,

Rodhiyah,

Luthfianti

et al. 2024

J. Phys.: Conf. Ser.

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“…Notably, hydrogels showcase exceptional reactivity to various stimuli, including pH, temperature, biological molecules, electric and magnetic fields, and solution ionic strength [2,8]. These characteristics indicate hydrogels with 'smart' properties, which are especially suitable for various biomedical applications, such as tissue engineering, wound dressings, pharmaceutical applications, contact lenses, and potential edible electronic devices [9][10][11][12][13][14][15][16]. Smart hydrogels are advanced materials that can intelligently and controllably release therapeutic agents (bioactive compounds) in response to environmental stimuli.…”

Section: Introductionmentioning

confidence: 99%

Bioactive compounds-loaded polyvinyl alcohol hydrogels: advancements in smart delivery media for biomedical applications

Luthfianti,

Waresindo,

Edikresnha

et al. 2024

Mater. Res. Express

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The paper initially focuses on the characteristics of Polyvinyl Alcohol (PVA) hydrogel as smart delivery media, such as chemical stability, biocompatibility, and capacity for controlled release of bioactive compounds. Then, it discusses the effect of loading bioactive compounds into PVA hydrogel, considering their stability of delivery media, controlled release, and targeted delivery, enhancing therapeutic outcomes. Loading bioactive compounds such as diphlorethohydroxycarmalol (DPHC), curcumin, carotenoids, andrographolide, and flavonoids into PVA hydrogels can enhance biomedical functionalities. These functionalities include improved drug delivery, wound dressing efficacy, tissue engineering potential, and contact lens applications. Further, while previous review papers have extensively covered aspects such as the source of bioactive compounds, extraction methods, synthesis of PVA hydrogel, and various biomedical applications, there remains a gap in the literature in which no studies have systematically explored the loading of bioactive compounds into PVA hydrogel. This targeted investigation distinguishes our work from previous studies and contributes a novel perspective to the expanding hydrogel market. In light of the projected compound annual growth rate of 7.15% in the hydrogel market from 2021 to 2028, this study provides a pioneering overview of recent advancements in bioactive compound-loaded PVA hydrogels. Finally, this review outlines the challenges in optimizing bioactive compound-loaded PVA hydrogels' performance and their biomedical application. In the future direction, this review explores their potential in smart delivery media, such as optimizing the loading efficiency and releasing kinetics to specific target therapeutic, crosslinking with double or triple network hydrogels, and convergence of nanotechnology with hydrogel that become frontiers in precision medicine.

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A guanosine/konjac glucomannan supramolecular hydrogel with antioxidant, antibacterial and immunoregulatory properties for cutaneous wound treatment

Zhang,

Chen,

Zhao

et al. 2024

Carbohydrate Polymers

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Konjac glucomannan-based hydrogels with health-promoting effects for potential edible electronics applications: A mini-review

Cited by 9 publications

References 86 publications

Enhanced Superabsorbency of Cellulose-Based Hydrogels in NaOH Solution: Synthesis, Characterization, and Performance Evaluation

Enhanced Superabsorbency of Cellulose-Based Hydrogels in NaOH Solution: Synthesis, Characterization, and Performance Evaluation

Bioactive compounds-loaded polyvinyl alcohol hydrogels: advancements in smart delivery media for biomedical applications

A guanosine/konjac glucomannan supramolecular hydrogel with antioxidant, antibacterial and immunoregulatory properties for cutaneous wound treatment

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