Abstract:In the near future several new immunosuppressive substances will be available: Cyclosporin G, IMM125 (both are new derivates of Cyclosporin A), FK506, Rapamycin, Leflunomid, Mycophenolic acid (RS-61443), Bredinin (Mizorinin), Brequinar, Deoxyspergualin and several new monoclonal antibodies (anti-CD4, anti-II-2-Receptor, anti-CD8, anti-CD45, anti-ICAM1 and others). Side-effects of immunosuppressants are classified in 1) relative drug-specific or 2) unspecific effects of over-immunosuppression (infections and ma… Show more
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