Komplikationen bei peripherer Regionalanästhesie

Neuburger, M.; Büttner, Johannes

doi:10.1007/s00101-011-1955-3

Cited by 17 publications

(6 citation statements)

References 95 publications

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“…This mixture contained 50 mg of lidocaine and 37.5 mg of ropivacaine. It is evident that the need for adjuvant epinephrine in addition to the anesthetics mixture in previous research [3] stemmed from the probable summary effect of system toxicity of both anesthetic agents [2] and due to the sciatic nerve block performed in combination with a femoral nerve block. To date, the reduced volume and amount of local anesthetic agents per blockage has been impossible because blockades were performed only with the use of an electric stimulator of the peripheral nerves.…”

Section: Discussionmentioning

confidence: 99%

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A comparison of the onset time of complete blockade of the sciatic nerve in the application of ropivacaine and its equal volumes mixture with lidocaine: a double-blind randomized study

Valery¹,

Marochkov²

2013

Korean J Anesthesiol

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BackgroundThe purpose of the current study is to create a new mixture of local anesthetics-one with a short time of block development and short action term (5 ml of 1% lidocaine solution) and another with a longer time of anesthesia development and a long analgetic effect (5 ml of 0.75% ropivacaine)-for use during surgical operations on extremities. The primary end point was the development of the complete sensory block of the sciatic nerve.MethodsSixty blocks of sciatic nerve were used in a double-blind randomized research, under ultrasonic guidance, using an electric stimulator with the peripheral nerves. Sixty patients were divided into 3 equal groups. In the first group, a sciatic nerve block was performed with 5 ml of 0.75% ropivacaine solution (37.5 mg); in the second group, 10 ml of 0.75% ropivacaine solution (75 mg) was used and, in the third group, a mixture of 5 ml of 0.75% ropivacaine (as above) and 5 ml of 1% lidocaine solution (50 mg) was used. The assessment of the time required for developing sensory and motor blocks was carried out from the beginning of local anesthetic solution injection in the fascial sheath of the sciatic nerve.ResultsDemographic data of patients were identical in the three sample groups. The time required for achieving a complete motor and sensory block was reduced due to the mix of the 1% lidocaine solution with the 0.75% ropivacaine solution. The time required for achieving a complete sensory block in groups treated with 5 and 10 ml ropivacaine was 45 (40-48) and 30 (28-30) min, respectively, in contrast with 12 (10-13) min when the mixture of anesthetics was applied (P < 0.01). There was no difference in analgesic duration in the postoperative period among groups at P > 0.05.ConclusionsThe mixture of 5 ml of 1% lidocaine with 5 ml of 0.75% ropivacaine leads to a reduction in the time required for the development of complete sensory and motor blocks of the sciatic nerve, without reducing postoperative analgesia time.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A comparison of the onset time of complete blockade of the sciatic nerve in the application of ropivacaine and its equal volumes mixture with lidocaine: a double-blind randomized study

Valery¹,

Marochkov²

2013

Korean J Anesthesiol

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“…An anesthetist's arsenal includes several local anesthetics for carrying out regional anesthesia, and these anes-thetics require different times for achieving complete sensory and motor blocks as well as different acting times [1]; attempts to mix anesthetics with different properties were done earlier with the aim of summarizing their useful effects. The toxic action of local anesthetics, appearing as a result of unpremeditated intravascular injection as well as a result of preparation absorption, required research in order to identify low doses of local anesthetics for effectively blocking peripheral nerves [2]. Different local anesthetics with different durations of action are used to block the sciatic nerve [1] [2].…”

Section: Introductionmentioning

confidence: 99%

“…The toxic action of local anesthetics, appearing as a result of unpremeditated intravascular injection as well as a result of preparation absorption, required research in order to identify low doses of local anesthetics for effectively blocking peripheral nerves [2]. Different local anesthetics with different durations of action are used to block the sciatic nerve [1] [2]. The latter fact is of great importance not only for duration of surgery, but also for postoperative analgesia.…”

Section: Introductionmentioning

confidence: 99%

Reducing the Dose of Local Anesthetic Reduces the Duration of Analgesia—Myth or Reality: A Double-Blind Randomized Study

Valery¹,

Aliaksei²

2015

OJAnes

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Background: The aim of the study is to determine the effect of a reduction in dose of local anesthetic blockade on the development of the sciatic nerve. Methods: Forty blocks of sciatic nerve were used in a double-blind randomized research, under ultrasonic guidance, using an electric stimulator with the peripheral nerves. Forty patients were divided into 2 equal groups. In the first group, a sciatic nerve block was performed with 5 ml of 0.75% ropivacaine solution (37.5 mg); in the second group, 10 ml of 0.75% ropivacaine solution (75 mg) was used. The assessment of the time required for developing sensory and motor blocks was carried out from the beginning of local anesthetic solution injection in the fascial sheath of the sciatic nerve. Results: Demographic data of patients were identical in the two sample groups. The time required for achieving a complete sensory block in groups treated with 5 and 10 ml ropivacaine was 45 (40; 48) and 30 (28; 30) min, respectively, (р < 0.01). There was no difference in analgesic duration in the postoperative period among groups at p > 0.05. Conclusions: Complete blockade of the sciatic nerve is developed using 5 ml of 0.75% ropivacaine. Reducing the dose of ropivacaine prolongs the latent period of the LA during the blockade of the sciatic nerve. Time of postoperative analgesia was not significantly changed.

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“…Nach entsprechen der NutzenRisikoAbwägung können sie auch bei Patienten durchgeführt werden, die unter einer Thromboseprophylaxe bzw. einer antithrombotischen Medikation stehen [33].…”

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2016

Handchir Mikrochir plast Chir

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Komplikationen bei peripherer Regionalanästhesie

Cited by 17 publications

References 95 publications

A comparison of the onset time of complete blockade of the sciatic nerve in the application of ropivacaine and its equal volumes mixture with lidocaine: a double-blind randomized study

A comparison of the onset time of complete blockade of the sciatic nerve in the application of ropivacaine and its equal volumes mixture with lidocaine: a double-blind randomized study

Reducing the Dose of Local Anesthetic Reduces the Duration of Analgesia—Myth or Reality: A Double-Blind Randomized Study

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