Kognitive Stimulation und Musikintervention bei stationär versorgten Menschen mit Demenz

Liesk, Jennifer; Hartogh, Theo; Kalbe, Elke

doi:10.1007/s00391-014-0661-6

Cited by 17 publications

(4 citation statements)

References 17 publications

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“…[ 69 , 70 ] But quite a number of trails were restricted by appropriate endpoints, which resulted in this individually cognitive interventions lack of the relevant endpoints whose efficacy we must adopt to analysis. Therefore, from our conclusion above, PE, MT, CCT all have beneficial effects on older adults with AD and MCI, especially PE [ 58 , 71 ] and MT [ 72 , 73 ] as relatively obtained easily interventions. AD and MCI are progressive neurodegenerative disorders, and are still incurable.…”

Section: Discussionmentioning

confidence: 84%

Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment

Liang¹,

Xu²,

Lü

et al. 2018

Medicine

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Background:The increasing prevalence of Alzheimer disease (AD) emphasizes the need for effective treatments. Both pharmacological therapies such as nutrition therapy (NT) and nonpharmacologic therapies including traditional treatment or personalized treatment (e.g., physical exercise, music therapy, computerized cognitive training) have been approved for the treatment of AD or mild cognitive impairment (MCI) in numerous areas.Methods:The aim of this study was to compare 4 types of interventions, physical exercise (PE), music therapy (MT), computerized cognitive training (CCT), and NT, in older adults with mild to moderate AD or MCI and identify the most effective intervention for their cognitive function. We used a system of search strategies to identify relevant studies and include randomized controlled trials (RCTs), placebo-controlled trials evaluating the efficacy and safety of 4 interventions in patients with AD or MCI. We updated the relevant studies which were published before March 2017 as a full-text article. Using Bayesian network meta-analysis (NMA), we ranked cognitive ability based objectively on Mini-Mental State Examination (MMSE), and assessed neuropsychiatric symptoms based on Neuropsychiatric Inventory (NPI). Pairwise and network meta-analyses were sequentially performed for efficacy and safety of intervention compared to control group through RCTs included.Results:We included 17 RCTs. Fifteen trials (n = 1747) were pooled for cognition and no obvious heterogeneity was found (I2 = 21.7%, P = .212) in NMA, the mean difference (MD) of PE (MD = 2.1, confidence interval [CI]: 0.44–3.8) revealed that PE was significantly efficacious in the treatment group in terms of MMSE. Five trials (n = 660) assessed neuropsychiatric symptoms with an obvious heterogeneity (I2 = 61.6%, P = .034), the MD of CCT (MD = −7.7, CI: −14 to −2.4), revealing that CCT was significantly efficacious in NPI.Conclusions:As the first NMA comparing different interventions for AD and MCI, our study suggests that PE and CCT might have a significant improvement in cognition and neuropsychiatric symptoms respectively. Moreover, nonpharmacological therapies might be better than pharmacological therapies.

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Section: Discussionmentioning

confidence: 84%

Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment

Liang¹,

Xu²,

Lü

et al. 2018

Medicine

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“…Participants of the intervention group visited the multi-domain CST program NEUROvitalis senseful , specifically developed for AD dementia patients, based on the previously published standardized cognitive training program NEUROvitalis ( Baller et al, 2009 ). Liesk et al (2015) previously concluded that the original NEUROvitalis cognitive training program designed for healthy elderly and patients with MCI included parts, e.g., psychoeducational elements and training of cognitive strategies, that are too challenging for AD dementia patients. Accordingly, these demanding parts were removed for NEUROvitalis senseful while the group games remained in the modified version.…”

Section: Methodsmentioning

confidence: 99%

Improved connectivity and cognition due to cognitive stimulation in Alzheimer’s disease

Behfar,

Richter,

Kural

et al. 2023

Front. Aging Neurosci.

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BackgroundDue to the increasing prevalence of Alzheimer’s disease (AD) and the limited efficacy of pharmacological treatment, the interest in non-pharmacological interventions, e.g., cognitive stimulation therapy (CST), to improve cognitive dysfunction and the quality of life of AD patients are on a steady rise.ObjectivesHere, we examined the efficacy of a CST program specifically conceptualized for AD dementia patients and the neural mechanisms underlying cognitive or behavioral benefits of CST.MethodsUsing neuropsychological tests and MRI-based measurements of functional connectivity, we examined the (neuro-) psychological status and network changes at two time points: pre vs. post-stimulation (8 to 12 weeks) in the intervention group (n = 15) who received the CST versus a no-intervention control group (n = 15).ResultsAfter CST, we observed significant improvement in the Mini-Mental State Examination (MMSE), the Alzheimer’s Disease Assessment Scale, cognitive subsection (ADAS-cog), and the behavioral and psychological symptoms of dementia (BPSD) scores. These cognitive improvements were associated with an up-regulated functional connectivity between the left posterior hippocampus and the trunk of the left postcentral gyrus.ConclusionOur data indicate that CST seems to induce short-term global cognition and behavior improvements in mild to moderate AD dementia and enhances resting-state functional connectivity in learning- and memory-associated brain regions. These convergent results prove that even in mild to moderate dementia AD, neuroplasticity can be harnessed to alleviate cognitive impairment with CST.

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“…Körperliche Aktivität hingegen ist ein potenter Schutzfaktor, um das Morbiditäts-und Mortalitätsrisiko zu senken [4]. Niedrigschwellige aktivierende Bewegungsangebote, insbesondere in Verbindung mit Musik, wie die aktivierende Pflege, können die Agitiertheit bei Demenz als eine Ressource nutzen, um zu Bewegungsübungen zu motivieren und sind eine kostengünstige Alternative zur medikamentösen Sedierung bei Agitiertheit [5]. Aktivierende Pflege ist ein sektorenüberreifendes, interdisziplinäres Angebot von qualifizierten Pflegenden und Betreuungskräften, das bei den zu Pflegenden ressourcenorientiert die Alltagskompetenz fördert.…”

Section: Körperliche Aktivität Wirkt Präventivunclassified

Geschlechtssensible Aktivierung von demenziellen Menschen in Pflegeeinrichtungen

Morgenstern¹,

Riedel²

2021

PPH

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Kognitive Stimulation und Musikintervention bei stationär versorgten Menschen mit Demenz

Cited by 17 publications

References 17 publications

Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment

Comparison of multiple interventions for older adults with Alzheimer disease or mild cognitive impairment

Improved connectivity and cognition due to cognitive stimulation in Alzheimer’s disease

Geschlechtssensible Aktivierung von demenziellen Menschen in Pflegeeinrichtungen

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