Koebner Phenomenon in Lichen sclerosus et atrophicus

Pock, Lumír

doi:10.1159/000247872

Cited by 26 publications

(13 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Palminteri et al found lichen sclerosus to be a major cause of long urethral and penile strictures [14], and it is suggested that distal obstruction such as that from lichen sclerosus or meatal stenosis leads to high pressure voiding and inflammation of the periurethral glands, causing progression of stricture disease [15, 16]. This is similar to the Koebner phenomenon, which is thought to be a factor in the formation of lichen sclerosus in the phimotic penis [17, 18]. …”

Section: Discussionmentioning

confidence: 99%

Incidence of Urethral Stricture in Patients with Adult Acquired Buried Penis

Liaw

Rickborn

McClung

2017

Advances in Urology

View full text Add to dashboard Cite

Introduction. Concealed-buried penis is an acquired condition associated with obesity, challenging to both manage and repair. Urethral stricture is a more common disorder with multiple etiologies. Lichen sclerosus is a significant known cause of urethral stricture, implicated in up to 30%. We hypothesize that patients with buried penis have a higher rate of urethral stricture and lichen sclerosus than the general population. Methods. We retrospectively reviewed a single surgeon's (CM) case logs for patients presenting with a buried penis. All patients were evaluated for urethral stricture with cystoscopy or retrograde urethrogram either prior to or at the time of repair for buried penis. Those that had surgical repair or biopsy were reviewed for presence of lichen sclerosus. Results. 39 patients met inclusion criteria. Of these, 13 (33%) had associated stricture disease. The location of the strictures was bulbar urethra (38%), penile urethra (15%), and meatus or fossa navicularis (62%). Five patients had lichen sclerosus and urethral stricture disease, while 3 had lichen sclerosus without stricture. 11/13 stricture patients were treated. Six underwent dilation, 3 underwent meatotomy, and 2 underwent urethroplasty. No significant recurrences of stricture were seen. Conclusion. Patients with a concealed penis are more likely than the general population to have a urethral stricture and/or LS. Patients presenting with concealed penis should also be evaluated for a urethral stricture.

show abstract

Section: Discussionmentioning

confidence: 99%

Incidence of Urethral Stricture in Patients with Adult Acquired Buried Penis

Liaw

Rickborn

McClung

2017

Advances in Urology

View full text Add to dashboard Cite

show abstract

“…Like psoriasis, vulval lichen sclerosus can express itself in areas of trauma or scarring. 9 In predisposed children, it is thought that sexual abuse may trigger vulval lichen sclerosus. 10 Cases have been reported in areas affected by radiotherapy 11 and sunburn.…”

Section: Discussionmentioning

confidence: 99%

Clinical review of 202 patients with vulval lichen sclerosus: A possible association with psoriasis

Simpkin

Oakley

2007

Aust J Dermatology

View full text Add to dashboard Cite

Two hundred and two patients with clinically typical or biopsy-confirmed vulval lichen sclerosus were reviewed either at consultation (75%) or by retrospectively examining their chart. At diagnosis, 79% were 50 years or older. Ninety-six per cent complained of itching, pain and/or dyspareunia. Lichen sclerosus most often affected the labia minora and perineum but 50% had perianal and 13% had extragenital disease. Thirty-five patients gave a history of psoriasis (17%), which affected the vulval area in 10. Thyroid disease was reported in 39 patients (19%), and 33 gave a family history of thyroid disease. Of those tested (142), 20% had elevated thyroid antibodies. Topical clobetasol propionate was very effective but at least intermittent treatment was required long term in 85%. At follow up, 101 of 185 patients (56%) were asymptomatic but 22 (12%) continued to have moderate-to-severe symptoms. Thyroid disease and psoriasis are common associated conditions.

show abstract

“…Stomal stenosis is more common in patients with lichen sclerosus, 6 which is not surprising as the disease is believed to show the Koebner phenomenon, which is the tendency of some skin diseases to develop in traumatized tissue. 7 The other common reason for revision is to deepen the glans cleft, which had shallowed out after a first stage procedure. We suspect that there is a natural tendency for shallowing out of the glans cleft to occur anyway but wonder if shrinkage of the graft had a part in this as well.…”

Section: Discussionmentioning

confidence: 99%