Knowledge of Antimicrobial Resistance and Associated Factors Among Health Professionals at the University of Gondar Specialized Hospital: Institution-Based Cross-Sectional Study

Abstract

BackgroundAntimicrobial resistance is one of the many health challenges worldwide, particularly in resource-limited countries like Ethiopia. Increasing knowledge of health professionals can reduce the occurrence of antimicrobial resistance. In this study, we determined the antimicrobial resistance knowledge and examined the associated factors among the University of Gondar Hospital health professionals.MethodsAn institution-based cross-sectional survey was carried out. The samples were randomly recruited. Statistical analysis was performed by using the statistical package for social sciences (SPSS) version 20 after entering the data using Epidemiological information (Epi-Info). To identify associated factors, the authors executed binary logistic regression and multivariate analysis wherein the statistical significance was decided at p < 0.05.ResultsFour hundred and twelve health professionals with ages ranging from 20-60 years and mean age of 29.9 years took part in the study. Fifty-three-point-four percent of participants were males. The majority of the total respondents (84.7%, 95% CI: 80.08–88.30) had good knowledge of antimicrobial resistance. It was found that being male (AOR = 1.94, 95% CI: 1.10, 3.52), a work experience of 6–10 years (AOR = 2.45, 95% CI: 1.28, 4.68), having 30–38working hours per week (AOR = 3.93, 95% CI: 1.38, 5.11), and antibiotic intake (AOR = 3.71, 95% CI: 1.75, 7.87) were significant factors of antimicrobial resistance knowledge.ConclusionIn the current study, about 84.5% of health professionals had good knowledge of antimicrobial resistance. Reducing working hours per week and increasing the experience of workers are recommended to increase the knowledge on AMR.

A systematic review and meta-analysis of antimicrobial resistance knowledge, attitudes, and practices: Current evidence to build a strong national antimicrobial drug resistance narrative in Ethiopia

“…Two authors (BW, and MO) independently assessed the methodological quality of each study. In this manner, the following major components were evaluated for studies reporting descriptive cross-sectional data only [26,27]: Q1) Was the sample frame appropriate to address the target population? Q2) Were study participants sampled in an appropriate way?…”

“…The sample size of the primary studies included in the review was significantly variable and ranged from (n = 91) [33] to (n = 571) [27]. Among the primary studies that reported gender [26][27][28][29][30][31][32][33][34][35][36][37][38], the majority of study participants (n = 2409) were male. All studies employed cross-sectional research designs [26][27][28][29][30][31][32][33][34][35][36][37][38][39].…”

“…Among the primary studies that reported gender [26][27][28][29][30][31][32][33][34][35][36][37][38], the majority of study participants (n = 2409) were male. All studies employed cross-sectional research designs [26][27][28][29][30][31][32][33][34][35][36][37][38][39]. The authors of the primary studies recruited study participants from healthcare workers [26,29,[37][38][39], patients [28,32], tertiary school students [30,35], community members /the general public [31,36], and livestock owners [27,33,34].…”

Knowledge, attitude and practice of healthcare workers towards antibiotic resistance during the COVID-19 pandemic

“… 43 On the other hand, a previous study reported that the higher knowledge among health professionals was associated with more working experience and fewer working hours. 51 Furthermore, the current study identified the associated factors with positive attitude, including, age, nationality and qualification. In Ethiopia, educational status and level of experience were associated with the attitude of the HCWs on hospital-acquired infection.…”

The Effort to Rationalize Antibiotic Use in Indonesian Hospitals: Practice and Its Implication

“…However, three hospitals still have not evaluated the AMR-CP team's ability to control antibiotic resistance in hospitals. Implementing an antibiotic stewardship program, leadership and management commitment, as well as the expertise of the team members, and an efective antimicrobial use policy helped to increase the rational use of antibiotics, decrease the prevalence of resistance, and provide signifcant economic benefts [32][33][34]. Terefore, AMR-CP should be supported and expanded so that antibiotics are used equally rationally throughout the hospital [35].…”