Knowledge Bases for Clinical Decision Support in Drug Prescribing – Development, Quality Assurance, Management, Integration, Implementation and Evaluation of Clinical Value

Eiermann, Birgit; Rahmner, Pia Bastholm; Korkmaz, Seher; Landberg, Carina; Lilja, Birgitta; Shemeikka, Tero; Vég, Anikó; Wettermark, Björn; Gustafsson, Lars L.

doi:10.5772/39458

Cited by 20 publications

(26 citation statements)

References 51 publications

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“…dosage information for certain age groups, indications and contraindications, information about drug-drug interactions (DDI), and knowledge about recommendations for certain medications. Information or knowledge in the latter category is ever growing and needs to be continuously updated [8][9][10]. Information technology has the potential to improve safety and efficiency in the medication management process [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Potential drug-related problems detected by electronic expert support system: physicians’ views on clinical relevance

Hammar

Lidström²,

Petersson

et al. 2015

Int J Clin Pharm

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Section: Introductionmentioning

confidence: 99%

Potential drug-related problems detected by electronic expert support system: physicians’ views on clinical relevance

Hammar

Lidström²,

Petersson

et al. 2015

Int J Clin Pharm

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“…Functionality of these systems range from providing only textual information about drugs to advanced logic for drug prescription based on patient current state. Such systems should be always tailored to the user needs [7]. Otherwise, they will not be accepted by physicians.…”

Section: Related Workmentioning

confidence: 96%

“…Moreover it should also be linked to other possible data sources, nomenclatures etc. Linkage is described as very important and time consuming in [7]. The problem of publishing and linking data on the Web has been adrressed by Tim Berners Lee in 2006 [2] when he proposed the so called Linked Data principles.…”

Section: Related Workmentioning

confidence: 99%

Linked Open Data for Healthcare Professionals

Kozák

Nečaský

Dědek³

et al. 2013

Proceedings of International Conference on Information Integration and Web-Based Applications &Amp; Services

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Physicians are overwhelmed with many different drugs and the need to know a lot of information about all of them. That is, however, almost impossible in the fast evolving area of pharmaceutical industry. Although many data sources about drugs are published on the Web, structured or unstructured, it is very time consuming to search through them. In this paper we identify these data sources according to information needs of physicians. We show that they can be relatively easily integrated using the Linked Data principles and, in case of unstructured data, NLP methods. An application on the top of the integrated data sets is presented as a possible tool for clinical decision support.

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“…These include drug information presented in computerized decision support systems (CDSSs), and linked to electronic health records (EHRs), to provide prescribers with patient specific dosing recommendations adjusted for renal impairment [2], potential drug interaction warnings [3] or other alerts for, for example, allergies or hypersensitivities or the suitability of the drug for use during pregnancy [4]. However, the effects of these integrated systems are still being discussed and under investigation, and there is a call for international standards for the systems and their content [5–9].…”

Section: Introductionmentioning

confidence: 99%

“…Despite this, increased efforts in the last decades have led to a limited number of CDSSs being incorporated consistently and safely into EHR systems with optimal links between drug information and patient characteristics [5]. However, in the absence of standardized and reliable drug information sources, individual countries are beginning to develop their own solutions to support the prescribers.…”

Section: Introductionmentioning

confidence: 99%

Physicians' reported needs of drug information at point of care in Sweden

Rahmner

Eiermann

Korkmaz

et al. 2011

Brit J Clinical Pharma

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Keywordsdecision support systems, drug information, drug labelling, focus group discussions, health services needs and demand, medical informatics ---------------------------------------------------------------------- WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• The computerization of health care has increased dramatically in the last decades in most European countries, but no standardization of any of the information support systems has been established on common ground. • The Summary of Product Characteristics (SmPC) is available all over Europe in written form and in some of the countries even electronically, but the structure and the content of the information vary.• The physicians' needs for useful and reliable information about drugs at point of care are a question of patient safety. WHAT THIS STUDY ADDS• A qualitative approach, in this case focus group discussions, proved advantagous compared with questionnaires. • Knowledge gained from physicians' experiences promoted the work of restructuring and organizing the e-SmPC database.• Most of the required information from physicians appeared to be possible to transfer from current SmPCs to clinical decisions support systems. AIMSRelevant and easily accessible drug information at point-of-care is essential for physicians' decision making when prescribing. However, the information available by using Clinical Decision Support Systems (CDSSs) often does not meet physicians' requirements. The Summary of Product Characteristics (SmPC) is statutory information about drugs. However, the current structure, content and format of SmPCs make it difficult to incorporate them into CDSSs and link them to relevant patient information from the Electronic Health Records. The aim of the study was to evaluate the perceived needs for drug information among physicians in Sweden. METHODSWe recruited three focus group discussions with 18 physicians covering different specialities. The information from the groups was combined with a questionnaire administered at the beginning of the group discussions. RESULTSPhysicians reported their needs for knowledge databases at the point of drug prescribing. This included more consistent information about existing and new drugs. They also wished to receive automatically generated alerts for severe drug-drug interactions and adverse effects, and to have functions for calculating glomerular filtration rate to enable appropriate dose adjustments to be made for elderly patients and those with impaired renal function. Additionally, features enhancing electronic communication with colleagues and making drug information more searchable were suggested. CONCLUSIONSThe results from the current study showed the need for knowledge databases which provide consistent information about new and existing drugs. Most of the required information from physicians appeared to be possible to transfer from current SmPCs to CDSSs. However, inconsistencies in the SmPC information have to be reduced to enhance their utility.

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Knowledge Bases for Clinical Decision Support in Drug Prescribing – Development, Quality Assurance, Management, Integration, Implementation and Evaluation of Clinical Value

Cited by 20 publications

References 51 publications

Potential drug-related problems detected by electronic expert support system: physicians’ views on clinical relevance

Potential drug-related problems detected by electronic expert support system: physicians’ views on clinical relevance

Linked Open Data for Healthcare Professionals

Physicians' reported needs of drug information at point of care in Sweden

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