Knowledge, Attitude and Practice of Community Pharmacists Regarding Antibiotic Use and Infectious Diseases: A Cross-Sectional Survey in Hungary (KAPPhA-HU)

Background: According to World Health Organization (WHO) drug use indicators manual, the patients' knowledge on dispensed medication is a crucial patient care indicator. There is a dearth of studies about patients' knowledge of dispensed medication at the primary health care facility. The objective of this study was to assess the knowledge of dispensed medication and associated factors among patients attending in the outpatient pharmacy of Chencha primary level hospital, Southwest Ethiopia. Methods: A facility-based cross-sectional study was employed among 403 patients attending in the outpatient pharmacy of Chencha primary level hospital. The data collection techniques were observation of dispensing process and face-to-face interview by using WHO patient care indicators and a structured questionnaire, respectively. Descriptive statistics, univariable and multivariable logistic regression were determined using the SPSS version 20. Results: A total of 403 patients participated which make the response rate 100%. Fifty-three (13.2%) patients had adequate knowledge on dispensed medication. The findings of multivariable logistic regression indicated that tertiary levels of education (AOR = 3.87; 95% CI [1.25, 11.96]), being private employee (AOR = 10.98; 95% CI [3.25, 37.04]), having severe perception of illness (AOR =3.77; 95% CI [1.43, 9.94]), having three or more visits (AOR =3.20; 95% CI [1.21, 8.44]) and being counseled by pharmacist (AOR = 10.02; 95% CI [4.45, 22.56]) significantly increased the odds of having a "adequate knowledge of medicines." Conclusion: This study showed inadequate level of knowledge of dispensed medicine among patients attending in outpatient pharmacy of Chencha primary level hospital. Patient education, employment status, number of visits, perception of illness, dispenser qualification and experience were the factors for knowledge of dispensed medicine. Dispensers need into account patients' perception of their illness of illness and frequency of visits during counseling.

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“…27 This implies that stakeholders need to provide on job training to pharmacy technicians on patient oriented pharmacy services. 28…”

Section: Discussionmentioning

confidence: 99%

<p>Knowledge on Dispensed Medications and Its Determinants Among Patients Attending Outpatient Pharmacy at Chencha Primary Level Hospital, Southwest Ethiopia</p>

Taddele

Adinew

Asfaw

2020

IPRP

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“…The MALDI Biotyper RTC 3.1 software (Bruker Daltonics, Bremen, Germany) and the MALDI Biotyper Library 3.1 were used for spectrum analysis. Antibiotic susceptibility testing is not routinely performed from AGNC isolates [14,15].…”

Section: Identification Of Isolatesmentioning

confidence: 99%

Epidemiology and species distribution of anaerobic Gram-negative cocci: a 10-year retrospective survey (2008-2017)

Gajdács

Urbán

2019

APH

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Introduction: The group of anaerobic Gram-negative cocci (AGNC) includes the genera Veillonella, Megasphaera, Anaeroglobus, Negativicoccus and Acidaminococcus. These bacteria are an integral part of the microbiome of humans but may be causative agents in various infectious processes. The available data on the epidemiology and significance of AGNCs is scarce. Aims: To assess and compare the prevalence of different species of AGNCs among inpatients and outpatients at the Albert Szent-Györgyi Clinical Center retrospectively, during a 10-year study period. Methods: Isolates containing AGNC were identified retrospectively by reviewing the online microbiology records of the Institute of Clinical Microbiology. Results: The median age of affected patients overall was 52 years (range: 1–90 years), with a male dominance. 59.79% of samples originated from inpatients. 572 individual AGNCs isolates were recovered from clinical samples, most of the isolated GNACs were Veillonella spp. (95.28%), Megasphaera and Acidaminococcus species accounted for a minority of isolates (2.79% and 1.93%, respectively), while Anaeroglobus and Negativicoccus species were not isolated. In the second half of the study period (2013-2017), 91.31% of isolates were identified on the species level (p<0.001) using MALDI-TOF MS. Conclusion: The current study represents a long-term surveillance study on the isolation frequency and trends among anaerobic Gram-negative cocci (AGNCs), isolated in the Southern Great Plain of Hungary, highlighting the beneficial effect of MALDI-TOF MS on the diagnostic efficacy of the laboratories.

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“…The emergence and worldwide spread of antibiotic-resistant bacterial pathogens is one of the most serious concerns for modern medicine and a major public health issue, which requires participation of all the relevant stakeholders on a global scale [1][2][3][4][5]. Infections caused by drug resistant bacteria are associated with decreased quality of life (QoL) in the affected patients, increased costs for the healthcare infrastructure, the necessity to use antibiotics that are more expensive or have a disadvantageous toxicity profile and an increased mortality rate overall [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Characterization of Resistance in Gram-Negative Urinary Isolates Using Existing and Novel Indicators of Clinical Relevance: A 10-Year Data Analysis

Gajdács

Bátori

Ábrók

et al. 2020

Life

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Classical resistance classifications (multidrug resistance [MDR], extensive drug resistance [XDR], pan-drug resistance [PDR]) are very useful for epidemiological purposes, however, they may not correlate well with clinical outcomes, therefore, several novel classification criteria (e.g., usual drug resistance [UDR], difficult-to-treat resistance [DTR]) were introduced for Gram-negative bacteria in recent years. Microbiological and resistance data was collected for urinary tract infections (UTIs) retrospectively, corresponding to the 2008.01.01–2017.12.31. period. Isolates were classified into various resistance categories (wild type/susceptible, UDR, MDR, XDR, DTR and PDR), in addition, two new indicators (modified DTR; mDTR and mcDTR) and a predictive composite score (pMAR) were introduced. Results: n = 16,240 (76.8%) outpatient and n = 13,386 (69.3%) inpatient UTI isolates were relevant to our analysis. Citrobacter-Enterobacter-Serratia had the highest level of UDR isolates (88.9%), the Proteus-Providencia-Morganella group had the highest mDTR levels. MDR levels were highest in Acinetobacter spp. (9.7%) and Proteus-Providencia-Morganella (9.1%). XDR- and DTR-levels were higher in non-fermenters (XDR: 1.7%–4.7%. DTR: 7.3%–7.9%) than in Enterobacterales isolates (XDR: 0%–0.1%. DTR: 0.02%–1.5%). Conclusions: The introduction of DTR (and its’ modifications detailed in this study) to the bedside and in clinical practice will definitely lead to substantial benefits in the assessment of the significance of bacterial resistance in human therapeutics.

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Knowledge, Attitude and Practice of Community Pharmacists Regarding Antibiotic Use and Infectious Diseases: A Cross-Sectional Survey in Hungary (KAPPhA-HU)

Cited by 81 publications

References 50 publications

<p>Knowledge on Dispensed Medications and Its Determinants Among Patients Attending Outpatient Pharmacy at Chencha Primary Level Hospital, Southwest Ethiopia</p>

<p>Knowledge on Dispensed Medications and Its Determinants Among Patients Attending Outpatient Pharmacy at Chencha Primary Level Hospital, Southwest Ethiopia</p>

Epidemiology and species distribution of anaerobic Gram-negative cocci: a 10-year retrospective survey (2008-2017)

Characterization of Resistance in Gram-Negative Urinary Isolates Using Existing and Novel Indicators of Clinical Relevance: A 10-Year Data Analysis

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