Knowledge and attitudes towards HIV vaccines among Soweto adolescents

Abstract

Background: To explore adolescent HIV risk perception, HIV vaccine knowledge, willingness to participate in future HIV vaccine clinical trials, and the factors that influence willingness to participate among high school students in Soweto, South Africa, we recruited school-going youth through randomly selected local high schools. All pupils within the selected schools from whom parental consent and child assent could be obtained were eligible for participation. A selfadministered, facilitated questionnaire was completed by all participants.

An update on human immunodeficiency virus vaccine preparedness studies

“…Two studies utilized a self-administered questionnaire (Chariyalertsak et al, 2011;de Bruyn et al, 2008;C. Beyrer, personal communication) and one study in South Africa utilized a self-administered visual analogue scale (VAS) (Giocos et al, 2008).…”

“…For example, in one study in South Africa, adolescents were defined as those aged 16-20 years (Middelkoop et al, 2008). Two studies examined high school students, with age ranges from 10 to 25 years (de Bruyn et al, 2008) and 14-21 years (Giocos et al, 2008). In addition, in the study by Middelkoop et al (2008), 71 % of adolescents were also in high school (K. Middelkoop, personal communication).…”

“…In the nine studies utilizing interviews, WTP ranged from 35 to 99.4 % (Table S1). In the two studies utilizing self-administered questionnaires (Chariyalertsak et al, 2011;de Bruyn et al, 2008), WTP in a hypothetical HIV vaccine trial ranged from 69.7 to 88.2 % (Table S1). In the one study that utilized a self-administered VAS, 79.5% of participants were WTP (Giocos et al, 2008).…”

“…Four studies examined adults and adolescents in South Africa. Besides adults (Middelkoop et al, 2008), populations examined in South Africa included adolescents (Middelkoop et al, 2008;Otwombe et al, 2011) Update on HIV vaccine preparedness studies data from our previous review of VPSs in the non-OECD countries, WTP in the South African studies ranged from 13 to 93 % in adolescents (Jaspan et al, 2006;Lindegger et al, 2007;Middelkoop et al, 2008) and 79.5-88.2 % in high school students as presented in the individual articles (de Bruyn et al, 2008;Giocos et al, 2008). Furthermore, in the study by Middelkoop et al (2008), 71 % of adolescents were in high school (K. Middelkoop).…”

“…In a study by Jaspan et al (2006) in South Africa, consent was obtained by adolescents and parents in their homes, and WTP using a self-administered questionnaire was 79 %. In the study by de Bruyn et al (2008), which utilized a facilitated selfadministered questionnaire, WTP in a hypothetical HIV vaccine trial by high-school students was 88.2 %. In this study, both parental and child consent was required for participation for those v18 years of age.…”