2023
DOI: 10.7759/cureus.42875
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Knowledge and Attitude of the General Population in Saudi Arabia Toward Weight Management Medications (WMMs): A Cross-Sectional Study

Abstract: Background: Over the past decades, the global prevalence of obesity has tripled, with the Kingdom of Saudi Arabia experiencing a notably higher rate of increase. While lifestyle modifications remain the first line of treatment, pharmacological interventions are often employed when dietary and exercise interventions prove insufficient. However, safety concerns, misuse, and limited knowledge about weight management medications (WMMs) pose serious challenges. Objectives: The objectives of this study we… Show more

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“…Establishing a clear cause-and-effect link between metabolic diseases, depression and medications is difficult because of their possible reciprocal relationship, shared underlying mechanisms and individual differences. Further research is needed to better understand both these complex interactions; the possible clinical impact of GLP-1 RAs on behavioral and non-behavioral addictions; and the safety profile [135] of these molecules. Finally, one issue looming at the door, still largely ignored in social media and public discourse, is that despite the current hype, GLP-1 RAs may be losing effects over time and rebound mechanisms in terms of weight loss and behavioral outcomes should be expected, as it has been here suggested by a few social media users.…”
Section: Discussionmentioning
confidence: 99%
“…Establishing a clear cause-and-effect link between metabolic diseases, depression and medications is difficult because of their possible reciprocal relationship, shared underlying mechanisms and individual differences. Further research is needed to better understand both these complex interactions; the possible clinical impact of GLP-1 RAs on behavioral and non-behavioral addictions; and the safety profile [135] of these molecules. Finally, one issue looming at the door, still largely ignored in social media and public discourse, is that despite the current hype, GLP-1 RAs may be losing effects over time and rebound mechanisms in terms of weight loss and behavioral outcomes should be expected, as it has been here suggested by a few social media users.…”
Section: Discussionmentioning
confidence: 99%