Klinische und erbbiologische Beobachtungen an Lichtkranken

Hoede, Karl

doi:10.1007/bf02281376

Cited by 2 publications

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“…In the literature 346 cases of atypical fibroxanthoma of the skin are available for study. They include lesions referred to as fibrosarcoma (Halpert & Hackney, 1949), paradoxical fibrosarcoma (Bourne, 1963), pseudosarcomatous dermatofibroma (Levan et al, 1963), pseudosarcomatous xanthofibroma (Hoede & Korting, 1968), pseudosarcomatous reticulohistiocytoma (Gordon, 1964) and pseudosarcoma (Finlay-Jones, Nicoll & ten Seldam, 1971;Samitz, 1967;Vakilzadeh & Rupee, 1970;Woyke et al, 1974). Many cases were reported in retrospect.…”

Section: Discussionmentioning

confidence: 99%

Atypical fibroxanthoma of the skin.

Starink¹,

Hausman²,

Delden³

et al. 1977

Br J Dermatol

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A typical fibroxanthoma is a solitary tumour of the skin, which occurs mostly on sun-exposed areas in elderly people. The diagnosis can only be made with certainty on the typical histological findings, which suggest a bizarre malignant tumour. Although metastasizing tumours are reported in the literature, the authors believe that the true atypical fibroxanthoma is benign. Correct diagnosis obviates the need for unnecessary radical surgery. The possibility of atypical fibroxanthoma should always be considered when a histologically bizarre tumour is found on sun-damaged or irradiation-damaged skin in elderly patients or on previously traumatized sites. In this paper five cases are added to the 346 cases culled from the literature. Electron microscopic investigations in one case demonstrated cells with delicate cytoplasmic fibrils in small bundles. This does not necessarily suggest filaments of myofibroblasts, as has been previously reported.

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