“…We observed a significant decrease in the steady state mRNA levels for each of these transcripts in the I3KO/MLL-Af4 Lin-cells, confirming our RNA sequencing results ( Figure 5E). In CD11b+ cells, we selected transcripts known to play a role in Ras signaling, Ccnd1, Maf, Mafb Itga6, Klf4, and Akt3 (Brundage et al, 2014;Eychène et al, 2008;Lewis et al, 2019;Riverso et al, 2017;Takata et al, 2005;Wagle et al, 2018;Wu et al, 2019). As expected, these transcripts were decreased in I3KO/MLL-Af4…”