Klebsiella pneumoniae-induced multiple invasive abscesses

Abstract

Rationale:Klebsiella pneumoniae infection can induce multiple invasive abscesses, and the invasive infection is severe and life-threatening.Patient concerns:A 69-year-old previously healthy Chinese male presented with fever, chill, backache, and ocular pain.Diagnosis:The blood culture results indicated Klebsiella pneumoniae of the K1 serotype. Multiple invasive abscesses in liver, lung, eye, soft tissue, and central nervous system were identified by imaging examination. Subsequently, the patient experienced right ocular pain accompanied by visual disturbance. Tyndall sign was strongly positive, and lens opacity was observed by the ophthalmologist.Interventions:Full-dose and long-term treatment with meropenem was performed. Intraventricular injection of glass and anterior chamber puncture with antibiotics were performed twice. The patient also underwent an evacuation of the brain abscess.Outcomes:The patient's headache and lumbar backache were relieved, his ophthalmodynia disappeared, and his vision recovered after nearly 3 months of treatment.Lessons:Imaging examination is very important for severe Klebsiella pneumoniae infection. The choice of antibiotics is complex, and the antimicrobial regimen should be adjusted according to the assessment of illness and the therapeutic effect. Surgical intervention must be considered for patients with multiple invasive abscesses.

Pelvic inflammatory disease and causative pathogens in older women in a medical center in eastern Taiwan: A retrospective cross-sectional study

“…K . pneumonia can cause a severe infection, such as meningitis or brain abscess, and can be life-threatening which needs advanced antibiotics treatment [ 23 ]. The previous study explored endocervical culture from 100 women and they found Klebsiella pneumonia occupied 2% of the study women [ 24 ].…”

A 54‐year‐old healthy patient with meningitis and conjunctivitis

“…In current practice, hypermucoviscosity KP serotype are diagnosed by string test. 1,2 The diagnosis may be confirmed by identifying capsular serotype via polymerase chain reaction assay. 1,2 Hypervirulent KP (hvKP) is defined by multiple organ localizations, in a few hours, very often in a healthy individual.…”

“…1,2 The diagnosis may be confirmed by identifying capsular serotype via polymerase chain reaction assay. 1,2 Hypervirulent KP (hvKP) is defined by multiple organ localizations, in a few hours, very often in a healthy individual. 1,2 Determination of hypervirulence is genetic and becomes frequent.…”

Severe invasive disease caused by hypervirulent Klebsiella pneumoniae: a case report

“…This is a rare clinical condition characterized by a primary liver abscess in combination with abscesses of other distant organ, including the eyes, lungs and central nervous system [4,5], and it most often occurs in patients with diabetes mellitus and hypertension [6]. The incidence of invasive K. pneumoniae liver abscess syndrome is high in Asia, and the prognosis is typically poor [7,8]. Prompt diagnosis and active treatment can improve the outcome.…”