“Kissing” Vegetation in a Rare Case of Infective Endocarditis by Gemella sanguinis

Chadha, Sameer; Chen, On; Shetty, Vijay; Sadiq, Adnan; Hollander, Gerald; Frankel, Robert; Shani, Jacob

doi:10.1097/maj.0b013e31827de7ba

Cited by 5 publications

(8 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our patient, there was no identifiable predisposing factor or source of infection. Her affected valve was the mitral valve while in the previous reports the aortic valve was affected in five cases [3, 8, 9, 11, 12], the mitral valve in two [7], and tricuspid valve in one [5]. Furthermore, in our case, the patient received intravenous antibiotics for a prolonged time, and the same treatment was also followed in 8 out of the 9 reported cases (for the remaining one, information is not available).…”

Section: Discussionmentioning

confidence: 97%

“…They are normal commensals of the oral cavity and the gastrointestinal tract [4, 6]. Gemella sanguinis was first described in 1998 [6] and has been reported once to be the cause of prosthetic joint infection [13] and nine times to be the cause of infective endocarditis [3, 5–12].…”

Section: Discussionmentioning

confidence: 99%

“…One patient died because of intracerebral bleeding caused by a ruptured cerebral mycotic aneurysm [8]. In the other seven cases, all the patients needed prosthetic valve replacement surgery [3, 5, 7, 9–12]. Overall, 40–50% of patients with infective endocarditis underwent prosthetic valve replacement surgery [14].…”

Section: Discussionmentioning

confidence: 99%

“…[3]. These species are catalase-negative, Gram-positive cocci [4], and among them, Gemella sanguinis has been reported as a cause of infective endocarditis in nine cases [3, 5–12]. All of the survivors not only received antimicrobial therapy but also underwent valve replacement [3, 5–12].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A Case Report of Successful Conservative Treatment for Infective Endocarditis Caused byGemella sanguinis

Emmanouilidou

Voukelatou

Vrettos

et al. 2019

Case Reports in Infectious Diseases

View full text Add to dashboard Cite

Infective endocarditis is defined as an infection of a native or prosthetic heart valve, the endocardial surface of the heart, or an indwelling cardiac device. Among the miscellaneous emerging opportunistic bacteria that can cause infective endocarditis is Gemella sanguinis that has been reported as a cause of infective endocarditis in nine cases in the past. All of the survivors received antimicrobial therapy and underwent prosthetic valve replacement surgery while, in general, a proportion of 40–50% of the patients with infective endocarditis underwent valve surgery. Our case illustrates that valve surgery, in combination with the administration of antibiotics, is not the only therapeutic option for infective endocarditis due to Gemella sanguinis and that a conservative management with prolonged administration of parenteral antibiotics under close supervision of the patient can be an option.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A Case Report of Successful Conservative Treatment for Infective Endocarditis Caused byGemella sanguinis

Emmanouilidou

Voukelatou

Vrettos

et al. 2019

Case Reports in Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…Gemella haemolysans, Gemella bergeriae, Gemella sanguinis were mainly found on aortic valves [15-17,19-22,29,30, 33,34,38,39,43,44,49,52,54,56,57,59-61,63,68,69,71-77, 80-82,84,85,87,89,91,92] while Gemella morbillorum and Gemella taiwanensis were discovered predominately on the mitral valve. [16][17][18]21,22,25,[27][28][29]31,32,34,35,37,38,41,43,44,46,[48][49][50][51][52]56,58,67,68,70,71,74,75,[78][79][80][81]83,[86][87][88][89][90][91]…”

Section: Laboratory Testsmentioning

confidence: 99%

Risk Factors and Patient Profile of Infective Endocarditis due to <i>Gemella spp.</i>

Kariyanna

Sutarjono²,

Ellanti

et al. 2020

AJMCR

View full text Add to dashboard Cite

Background. The diagnosis of infective endocarditis is difficult, especially when it involves atypical organisms. Therefore, our study identified risk factors of infective endocarditis caused by rare pathogen, Gemella spp . Methods. A systematic review was conducted to investigate characteristics of endocarditis patients infected with Gemella spp. using the search term “ Gemella ” and “endocarditis.” Case reports were gathered by searching Medline/Pubmed, Google Scholar, CINAHL, Cochrane CENTRAL, and Web of Science databases. 83 articles were selected for review. Results. Five species of Gemella were identified. Typical patients were males between 31 and 45 years of age. On admission, patients had fever, tachycardia, and normal blood pressure. Common clinical manifestation other than fever included fatigue and weakness, chills and sweating, and nausea, vomiting, diarrhea, and weight changes. One in four reported a history of congenital heart disease, and a recent oral cavity infection. Laboratory tests reveal anemia, leukocytosis, and elevated erythrocyte sedimentation in all age groups, elevated C-reactive protein is observed among adult and geriatric populations only. Mitral and aortic valves were most commonly infected by Gemella spp. . The most common Gemella spp. -susceptible antibiotics were penicillin, vancomycin, cephalosporin, macrolide, and aminoglycosides. However, antibiotic resistance was observed against penicillin, aminoglycoside, and fluoroquinolone. Antibiotic course of at least six weeks resulted in superior clinical improvements than durations under six weeks. Finally, one in two patients underwent valve replacement or repair, with common complications affecting the cardiovascular, neurological, and renal systems. Finally, death occurred in 1 in 8 patients, half of which occurred post-surgical procedure, and the majority occurring equal to or greater than 1 week from admission. Conclusion. Our systematic review highlights the importance of considering rare pathogens, particularly in the presence of predisposing risk factors.

show abstract

A rare case of isolated mitral valve endocarditis by Gemella sanguinis: Case report and review of the literature

Sideris

Zimmermann

Ogami

et al. 2020

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

“Kissing” Vegetation in a Rare Case of Infective Endocarditis by Gemella sanguinis

Cited by 5 publications

References 2 publications

A Case Report of Successful Conservative Treatment for Infective Endocarditis Caused byGemella sanguinis

A Case Report of Successful Conservative Treatment for Infective Endocarditis Caused byGemella sanguinis

Risk Factors and Patient Profile of Infective Endocarditis due to <i>Gemella spp.</i>

A rare case of isolated mitral valve endocarditis by Gemella sanguinis: Case report and review of the literature

Contact Info

Product

Resources

About