Abstract:Bifurcation lesions are the most frequently approached complex coronary lesions in everyday interventional practice. Bifurcations complexity relies essentially on their very specific anatomy that is imperfectly handled by current coronary devices and, despite dedicated techniques and drug-eluting stents, percutaneous coronary interventions directed toward the treatment of bifurcations are technically demanding and require proper execution. Kissing balloon (KB) inflation was the first specific bifurcation techn… Show more
“…22 Technical improvements to the FKB technique have been proposed, including rewiring through cell struts near the carina, appropriate selection of balloon size (avoiding usage of smaller MV kissing balloon diameter than that for the deploying balloon), simultaneous balloon deflation in both vessels, and non-compliant balloon use. 23- 27 The FKB, using these technical considerations and newer generation DES, coupled with longer-term follow up, might be crucial to clarify the benefit of it in a 1-stent approach.…”
Section: Fkb Technique and The 1-stent Approachmentioning
110YAMAWAKI M et al.
Circulation JournalOfficial Journal of the Japanese Circulation Society http://www. j-circ.or.jp oronary bifurcation has been regarded as one of the most challenging lesion subsets due to poor clinical outcomes compared with non-bifurcated lesions. 1 Provisional intervention of the side branch (SB) after main vessel (MV) stenting is now the standard approach for most bifurcations. 2,3 Although the final kissing balloon technique (FKB) has been established as the first-line strategy for bifurcations treated with an elective 2-stent approach, 4,5 its efficacy in a 1-stent approach is presently under debate. 6,7 Randomized trials showed no benefit of FKB in a 1-stent approach; 8,9 however, the long-term clinical outcome remains unclear as limited data is currently available. 6,10 The purpose of the present study is to: (1) investigate the long-term outcomes after a 1-stent approach with and without FKB; and (2) to ascertain the clinical outcome after cross-over stenting without FKB in comparison with non-bifurcation patients.
MethodsThis study is a sub-analysis of the TAXUS Japan Postmarket Surveillance Study (TAXUS-PMS), which evaluated the safety and performance of a paclitaxel-eluting stent (PES; TAXUS
“…22 Technical improvements to the FKB technique have been proposed, including rewiring through cell struts near the carina, appropriate selection of balloon size (avoiding usage of smaller MV kissing balloon diameter than that for the deploying balloon), simultaneous balloon deflation in both vessels, and non-compliant balloon use. 23- 27 The FKB, using these technical considerations and newer generation DES, coupled with longer-term follow up, might be crucial to clarify the benefit of it in a 1-stent approach.…”
Section: Fkb Technique and The 1-stent Approachmentioning
110YAMAWAKI M et al.
Circulation JournalOfficial Journal of the Japanese Circulation Society http://www. j-circ.or.jp oronary bifurcation has been regarded as one of the most challenging lesion subsets due to poor clinical outcomes compared with non-bifurcated lesions. 1 Provisional intervention of the side branch (SB) after main vessel (MV) stenting is now the standard approach for most bifurcations. 2,3 Although the final kissing balloon technique (FKB) has been established as the first-line strategy for bifurcations treated with an elective 2-stent approach, 4,5 its efficacy in a 1-stent approach is presently under debate. 6,7 Randomized trials showed no benefit of FKB in a 1-stent approach; 8,9 however, the long-term clinical outcome remains unclear as limited data is currently available. 6,10 The purpose of the present study is to: (1) investigate the long-term outcomes after a 1-stent approach with and without FKB; and (2) to ascertain the clinical outcome after cross-over stenting without FKB in comparison with non-bifurcation patients.
MethodsThis study is a sub-analysis of the TAXUS Japan Postmarket Surveillance Study (TAXUS-PMS), which evaluated the safety and performance of a paclitaxel-eluting stent (PES; TAXUS
“…The authors examined the different haemodynamic scenarios provoked by the final kissing balloon (FKB) inflation performed with a proximal or a distal access to the SB. This procedure consists of the simultaneous expansion of two balloons in both the branches and usually concludes the PSB [7]. The haemodynamic influence of the FKB was also studied by Foin et al [8] comparing this technique with a simpler two-step sequential post-dilatation of the SB and MB.…”
One of the relevant phenomenon associated with in-stent restenosis in coronary arteries is an altered haemodynamics in the stented region. Computational fluid dynamics (CFD) offers the possibility to investigate the haemodynamics at a level of detail not always accessible within experimental techniques. CFD can quantify and correlate the local haemodynamics structures which might lead to in-stent restenosis. The aim of this work is to study the fluid dynamics of realistic stented coronary artery models which replicate the complete clinical procedure of stent implantation. Two cases of pathologic left anterior descending coronary arteries with their bifurcations are reconstructed from computed tomography angiography and conventional coronary angiography images. Results of wall shear stress and relative residence time show that the wall regions more prone to the risk of restenosis are located next to stent struts, to the bifurcations and to the stent overlapping zone for both investigated cases. Considering a bulk flow analysis, helical flow structures are generated by the curvature of the zone upstream from the stent and by the bifurcation regions. Helical recirculating microstructures are also visible downstream from the stent struts. This study demonstrates the feasibility to virtually investigate the haemodynamics of patient-specific coronary bifurcation geometries.
“…One of the most deeply investigated is the final kissing balloon inflation (FKBI) technique 11. In general, with the FKBI technique, two balloons are introduced over two separate guide wires: one balloon is positioned in the SB while the other is placed in the MB crossing the SB.…”
Section: Introductionmentioning
confidence: 99%
“…In general, with the FKBI technique, two balloons are introduced over two separate guide wires: one balloon is positioned in the SB while the other is placed in the MB crossing the SB. The balloons are inflated simultaneously, opening the SB while preventing geometric distortions in the MB 11. Currently, there is consensus that FKBI is mandatory in complex two-stent bifurcation techniques,12 based on non-randomised studies evaluating the crush13–15 and culotte16 two-stent techniques.…”
A lower cardiac death rate was observed in patients in whom FKBI was performed compared with a selection of patients in whom FKBI could not be performed, probably explained by an unbalance in the baseline risk profile of the patients. No differences were observed regarding the other clinical outcomes.
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