“…The kinetic model, by which the Aβ peptides form the amyloid fibrils, is believed to follow a nucleation-growth model, with a lag phase of several days [ 89 , 150 , 284 , 285 , 286 , 287 , 288 , 289 , 290 , 291 , 292 , 293 ]. Oligomerization is very sensitive to amino-acid variations [ 123 , 294 , 295 ].…”