Kinetics of fluidized bed melt granulation—II: Modelling the net rate of growth

A priori prediction of aggregation efficiency and rate constant for fluidized bed melt granulation

“…Fig. 5 shows a comparison between the calculated aggregation rate constant and experimental data obtained from Tan et al (2006). The results confirm reasonable agreement between our model prediction and the reported experiment data.…”

“…Previous experimental investigations by Tan et al (2006) have shown that the bed temperature has two competing effects on the aggregation rate constant depending on the bed temperature: (i) enhanced binder spreading at low bed temperature, thus increasing the wet fractional coverage of the particle, or in other words, increasing the probability of granule-granule contacts at the wet surface (ii) granules breakage at high bed temperature close to the binder melting point, which is believed to be due to increasing probability of liquid bridge rupture with decreasing the binder viscosity. While the above proposed formulations indeed takes into consideration the effect of bed temperature on the aggregation rate constant through the binder solidification term, it lacks the appropriate formulation to account for this effect on the probability of liquid bridge rupture as the bed temperature increases (i.e.…”

Kinetics of fluidised bed melt granulation I: The effect of process variables

“…These results will be subsequently used for a one-dimensional population balance modelling to extract the effective aggregation rate constant of the process in the subsequent article (Tan et al, 2004a). The present work deals with a simple model system of polyethylene glycol (PEG) granulating with glass ballotini in a small-scale fluidised bed granulator, with the attempt to study the impact of binder spray rate, bed temperature, atomising pressure (binder droplet size) and fluidising air flow rate on granule growth behaviour.…”

Modelagem Do Processo De Granulação De Polvilho Doce Em Leito Fluidizado Pulsado Por Balanço Populacional

“…Diversos autores trabalharam com modelos baseados em balanços populacionais para simulação de processos de granulação, por esses modelos apresentarem bons resultados e apresentarem alta eficiência computacional (PEGLOW et al, 2007;TAN et al, 2004;TAN et al, 2006;LIU e LITSTER, 2002). Mais especificamente, os modelos de balanço populacional são balanços numéricos em torno de cada intervalo da distribuição de tamanho de partículas, baseado na conservação do número de partículas.…”