Kinetic study of the ruthenium(III)-catalyzed oxidation of glycine by N-bromophthalimide in acidic medium

Abstract

The kinetics of ruthenium(III) chloridecatalyzed oxidation of glycine by N-bromophthalimide (NBP) was studied in aqueous perchloric acid at 35°C. The results showed first-and zero-order behavior with respect to NBP and Gly, respectively. Ru(III) showed a catalytic effect on the reaction which followed first-order kinetics with respect to [Ru(III)] at a low concentration range and tended to zero order at high concentration range. The rates decreased with increase in the proton concentration, while chloride positively influenced the rate of the reaction. Two moles of NBP were required to oxidize one mole of Gly, and the products were identified as phthalimide (NHP), HCN, CO 2 , and Br -. Neither added NHP nor Br -influenced the reaction rate. Ionic strength and dielectric constant of the medium had no significant effect on the rate. Activation parameters were determined by studying the reaction at different temperatures. A reaction scheme of the catalytic oxidation is proposed.

Kinetic studies in the surfactant catalyzed oxidative deamination and decarboxylation of L-Valine by permanganate in sulphuric acid medium

“…Oxidation of valine by N-Bromophthalimide in presence of chlorocomplex of Pd(II),as Iridium (III) Chloride and Ruthenium(III) Chloride homogenous catalyst studied by Singh et al [7,8,9] . Deamination and decarboxylation in the chromium(III)-catalysed oxidation of L-valine by alkaline permanganate and analysis of chromium(III) in microscopic amounts by a kinetic method was studied by Kulkarni and coworkers [10] .Kinetic and mechanistic studies of oxidation of glycine and valine by Nbromosuccinimide using chloro complex of Rh(III) in its nano-concentration range as homogeneous catalyst investigated by Singh et al [11] .Kinetics and mechanisms of the permanganate oxidation of L-valine in neutral aqueous solutions was studied by Perez-benito et al [12] .…”

Kinetics of Oxidation of Amino Acids by a Newly Synthesized Oxidant, N-Chloropyrazinamide in Aqueous Acetic Acid Medium

“…Although a lot of works have been reported on the oxidation of amino acids by N-halo compounds [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] , the kinetic investigation on the oxidation of amino acids by N-chloropyrazinamide, a newly synthesized oxidant 23 , is not reported so far. Hence, in the present investigation, the kinetics of oxidation of alanine (Ala), glycine (Gly), leucine (Leu), phenyl alanine (Phe) and valine (Val) with N-chloropyrazinamide (NCPZA) in aqueous acetic acid medium in the presence of perchloric acid has been reported 26 .…”

Kinetics and Mechanism of Aquachlororuthenium (III) Catalyzed Oxidation of Tartaric Acid by Acid Bromate

“…The oxidation products depend on the type of oxidant and on the reaction medium. Kinetic studies on the oxidation of tartaric acid with different oxidants such as N-bromophthalimide [1][2][3][4][5][6][7], N-bromoacetamide [8], silver (II) [9], N-bromosuccinimide [10], Cr (VI) in aqueous perchloric acid medium [11], alkaline hexacynoferrate (III) [12], alkaline iodate [13] and chloramine -T [14][15][16] have been reported earlier. Potassium bromate [Br (V)] is known to be a powerful oxidizing agent with redox potentials of 1.44 V in acid medium and 0.61V in alkaline medium.…”