Abstract:Stereoselectivity in the mutual kinetic resolution (KR) of racemic 3,4-dihydro-3-methyl-2H- [1,4]benzoxazines and racemic 2-aryloxy propionyl chlorides was studied. Based on the results obtained, preparative methods for single enantiomers of a series of 2-aryloxy propionic acids via acylative KR of their racemates with enantiopure (S)-3,4-dihydro-3-methyl-2H- [1,4] benzoxazines have been proposed.
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