Kinetic resolution of chiral alcohols in bifunctional membrane exhibiting enzyme activity and enantioselective permeation

Catalysis of an ester hydrolysis applying molecularly imprinted polymer shells based on an immobilised chiral template

“…The main investigated reaction with respect to enantioselectivity of MIP catalysts is the hydrolysis of enantiomeric esters [23][24][25][26]. Nevertheless, transesterifications can be catalysed as well with MIPs, as shown by Koter and Ceynowa [27]. This paper demonstrates for the first time the use of an immobilised chiral TSA-template for the synthesis of a catalytically active MIP.…”

“…Only a few examples have been presented in the literature demonstrating such an enantioselectivity of catalytically active molecularly imprinted materials [19][20][21][22][23][24][25][26][27]. Already in 1977, Wulff et al described chiral cavities generated in enzyme-analogue synthetic polymers [19].…”

Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003

“…1362 Transport was faster for membranes formed with more template. The membranes were also derivatized with a lipase and used for enantioselective esterification of the imprinted template-the selectivity of the enzyme was amplified by the concentrating effect of the imprinted membrane.…”

Polyurea With L‐Lysinyl Residues as Components: Application to Membrane Separation of Enantiomers

“…environment in their main chains or in their side ones, [17][18][19][20][21][22][23][24][25][26][27][28] (iii) optical resolution with membrane with chiral helicity, [29] (iv) that with achiral membrane and affinity macroligand, such as bovine serum albumin (BSA), [30,31] by applying sieving effect, and (v) kinetic resolution with enzyme. [32,33] The authors' research group focused their attentions on chiral separation with molecularly imprinted membranes, [22,24] molecularly imprinted nanofiber membranes, [34,35]] membranes with chiral environment, [26] and membranes from chiral polyamides consisting of amino acid residues. [36,37] Amino acid residues, excepting glycine, are promising building blocks for chiral separation membranes since they have asymmetric center.…”