Kinetic of α-Amylase and Comparison its Inhibition by Ethanol and Aqueous Extracts of Otostegia persica, Salvia mirzayanii and Zataria multiflora

Effects of Salvia mirzayanii extract administration on hyperglycemia improvement in diabetic rats: The role of GLUT4, PEPCK and G6Pase genes

“…As preliminary data, these results mean that S. mirzayanii has an anti-diabetic effect. These data agreed with the findings about S. mirzayanii [ 18 , 19 , 31 ]. The hypoglycemic effects for the other species of salvia genus like S. hydrangea [ 32 ], S. officinalis [ 14 , 16 ], S. sahendicahas [ 33 ], S. miltiorrhiza [ 13 , 34 ] have also been reported in previous studies.…”

“…For example, Salvia is the largest genera of the Lamiaceae family, containing over 900 species worldwide that demonstrate different therapeutic activities to treat various diseases. The members of genus Salvia have important biological and pharmacological properties, e.g., astringent, antiseptic, spasmolytic, and anti-inflammatory effects [ [13] , [14] , [15] , [16] , [17] , [18] ]. Various species of Salvia were used in conventional medicine to treat diabetes [ 16 , 18 ].…”

“…The members of genus Salvia have important biological and pharmacological properties, e.g., astringent, antiseptic, spasmolytic, and anti-inflammatory effects [ [13] , [14] , [15] , [16] , [17] , [18] ]. Various species of Salvia were used in conventional medicine to treat diabetes [ 16 , 18 ]. In folk Iranian medicine, Salvia mirzayanii (locally called Bitter Moor) is a perennial plant that grows in southern and central parts of Iran.…”

“…In folk Iranian medicine, Salvia mirzayanii (locally called Bitter Moor) is a perennial plant that grows in southern and central parts of Iran. The extract of S. mirzayanii leaves was suggested for diabetes, and its antioxidant activity shows this effect [ [17] , [18] , [19] ]. The hypoglycemic activity of S. mirzayanii in diabetic patients was reported by Moein et al [ 19 ].…”

An investigationof the inhibitory effects of dichloromethane and methanol extracts of Salvia macilenta, Salvia officinalis, Salvia santolinifola and Salvia mirzayanii on diabetes marker enzymes, an approach for the treatment diabetes

“…These results are consistent with the findings of a study by Dr. Moein et al (2012) which showed that phenolic compounds in S.mirzayanii may be responsible for free radical scavengingand the prevention of disease such as cancer and cardiovascular disease, diabetes and aging [16]. It is also in line with Dr. Moein's 2018 study, which showed that aqueous-methanol fractions of S.mirzayanii inhibited α-amylase, but further studies were needed to determine the type of inhibition [17]. Study by Mohammad Reza Zarshenas in 2014 is consistent with the above mentioned results on diabetic model of rats, which showed that injection alcoholic extractof S.mirzayanii decrease blood glucose levels [18].…”