Kinetic model of Proteus mirabilis swarm colony development

Esipov, Sergei E.; Shapiro, James A.

doi:10.1007/s002850050100

Cited by 86 publications

(161 citation statements)

References 23 publications

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“…At the same time many papers investigate through experiments the precise nature and classi"cation of these patterns (Ohgiwari et al 1992;Shimada et al 1995;Nakahara et al 1996). On the other hand, the good agreement between experiments and continuum dynamic approaches of several papers (Chiu et al 1994;Shapiro 1995;Woodward et al 1995;Rauprich et al 1996;Esipov & Shapiro 1998) highlight the relevance of these approaches. The development of highly consistent theories for understanding the strategies adopted by the bacteria is of signi"cant interest.…”

Section: Introductionmentioning

confidence: 97%

The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

Bees¹,

Andresén²,

Mosekilde³

et al. 2000

Journal of Mathematical Biology

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Abstract. The rate of expansion of bacterial colonies of S. liquefaciens is investigated in terms of a mathematical model that combines biological as well as hydrodynamic processes. The relative importance of cell di!erentiation and production of an extracellular wetting agent to bacterial swarming is explored using a continuum representation. The model incorporates aspects of thin "lm #ow with variable suspension viscosity, wetting, and cell di!erentiation. Experimental evidence suggests that the bacterial colony is highly sensitive to its environment and that a variety of mechanisms are exploited in order to proliferate on a variety of surfaces. It is found that a combination of e!ects are required to reproduce the variation of bacterial colony motility over a large range of nutrient availability and medium hardness.

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Section: Introductionmentioning

confidence: 97%

The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

Bees¹,

Andresén²,

Mosekilde³

et al. 2000

Journal of Mathematical Biology

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“…Studies with Proteus indicated that overall colony patterns (Figure 2) reflect the operation of highly regular systems for cell differentiation and motility (Rauprich et al, 1996;Esipov and Shapiro, 1998). It is important to note that the strikingly symmetrical colony structure apparently does not have any intrinsic functionality.…”

Section: Personal History: Transposable Elements Adaptive Mutation Amentioning

confidence: 99%

Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology

Shapiro

2007

Studies in History and Philosophy of Science Part C: Studies in

170

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40 years experience as a bacterial geneticist have taught me that bacteria possess many cognitive, computational and evolutionary capabilities unimaginable in the first six decades of the 20 th Century. Analysis of cellular processes such as metabolism, regulation of protein synthesis, and DNA repair established that bacteria continually monitor their external and internal environments and compute functional outputs based on information provided by their sensory apparatus. Studies of genetic recombination, lysogeny, antibiotic resistance and my own work on transposable elements revealed multiple widespread bacterial systems for mobilizing and engineering DNA molecules. Examination of colony development and organization led me to appreciate how extensive multicellular collaboration is among the majority of bacterial species. Contemporary research in many laboratories on cell-cell signaling, symbiosis and pathogenesis show that bacteria utilize sophisticated mechanisms for intercellular communication and even have the ability to commandeer the basic cell biology of "higher" plants and animals to meet their own needs. This remarkable series of observations requires us to revise basic ideas about biological information processing and recognize that even the smallest cells are sentient beings.

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“…Not only is it thought that the swarmer cells have a role in the rapid expansion of the colony, but they may also be important for other reasons, such as increased resistance to predation (Ammendola et al, 1998). Swarming colony expansion has been observed to be either continuous and sustained (such as for colonies of S. liquefaciens; see below) or can occur in periodic bursts [such as for Proteus mirabilis; Rauprich et al (1996), Esipov and Shapiro (1998) and Czirok et al (2001)].…”

Section: Introductionmentioning

confidence: 99%

Quantitative Effects of Medium Hardness and Nutrient Availability on the Swarming Motility of Serratia liquefaciens

Bees

Andresén

Mosekilde

et al. 2002

Bulletin of Mathematical Biology

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We report the first controlled measurements of expansion rates for swarming colonies of Serratia liquefaciens under different growth conditions, combined with qualitative observations of the organization of the colony into regions of differentiated cell types. Significantly, the results reveal that swarming colonies of S. liquefaciens can have an increasing expansion rate with time. We compare and contrast the expansion rate results with predictions from a recent mathematical model which coupled key hydrodynamical and biological mechanisms. Furthermore, we investigate whether the swarming colonies grow according to a power law or exponentially (for large times), as suggested by recent theoretical results.

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Kinetic model of Proteus mirabilis swarm colony development

Cited by 86 publications

References 23 publications

The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

The interaction of thin-film flow, bacterial swarming and cell differentiation in colonies of Serratia liquefaciens

Bacteria are small but not stupid: cognition, natural genetic engineering and socio-bacteriology

Quantitative Effects of Medium Hardness and Nutrient Availability on the Swarming Motility of Serratia liquefaciens

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