Kinetic determination of morphine by means of Bray–Liebhafsky oscillatory reaction system using analyte pulse perturbation technique

Determination of experimental conditions for examination of analytes in Bray-Liebhafsky oscillatory reaction in open reactor conditions

“…S obzirom da je BL oscilatorna reakcija i dalje nepoznanica, ponašanje matrice pri perturbaciji analitom, može da doprinese i proširivanju saznanja o samom ocilatornom sistemu. Do sada je BL reakcija, u uslovima otvorenog reaktora, uspešno korišćena za određivanje koncentracije kvercetina [12,13], rutina [14], hesperidina [15], polimernog nosača [16], paracetamola [17], morfina [18], 6-O-acetilmorfina [19], askorbinske kiseline [20] , vitamina B grupe (B1, B2, B3 i B6) [21], mokraćne kiseline [22] i piroksikama [23] Cilj ovog rada je pronalaženje eksperimentalnih uslova u otvorenom reaktoru za ispitivanje širokog spektra analita u BL reakciji. Pronalaženje pomenutih uslova vrši se bifurkacionom analizom i predstavlja prvi korak u ispitivanju analita, njegovih fizičko-hemijskih svojstava, koncentracije, ali i mehanizma delovanja u BL sistemu.…”

Advances made by Belgrade's group in research of oscillatory reactions

“…Furthermore, various methods were developed for formal kinetics of homogenous oscillatory process (Anić et al 1986a;Anić et al 1987;Anić et al 1988;Anić et al 1996;Anić et al 2007), as well as for the stability analysis of the postulated models (Kolar- Anić et al 1995b;Schmitz et al 2000). All investigations were used for different purposes, starting with the development of new analytical methods Pejić et al 2003;Pejić et al 2005;Pejić et al 2006;Pejić et al 2007a;Pejić et al 2007b;Pejić et al 2007c;Pejić et al 2009;Pejić et al 2011;Pejić et al 2012;Pejić et al 2013;Pejić et al 2014a;Pejić et al 2014b;Pejić et al 2016;Vukojević et al 1999;Vukojević et al 2001) and the methods for determining the catalyst's activity Terlecki-Baričević et al 1995;Pejić et al 2001;Anić et al 2009;Maksimović et al 2011), as well as the influence of external fields on the evolution of the chemical oscillator (Stanisavljev et al 2004;Stanisavljev et al 2005;Stanisavljev et al 2006;Stanisavljev et al 2014) to modelling of biochemical processes (Jelić et al 2008;Jelić et al 2009;Čupić et al 2016b;Čupić et al in press;Kolar-Anić 2017d;Marković at. al 2011a;Čupić et al in press;Marković et al 2011b;…”

Kinetic Spectrophotometric Determination of Morphine in Pharmaceutical Samples

“…These include: spectrophotometry 5,6 , immuno chromatography 7 , potentiometry 8,9 , simultaneous voltammetric and amperometric 10 , gc-mass 1,11,26 , cyclicvoltametry and amperometry 12 , cyclicvoltametry 13,14 , sequential injection analysis 4 ,chemiluminescence 15 , kinetic potentiometric 9 , high performance liquid chromatography [16][17][18][19] , gas chromatography 20 , capillary electrophoresis 21 , ion mobility spectrometry 22,23 . These methods are efficient, but require expensive instrument and are expensive and many of them have needing time to complete the determination.…”