Kinetic and Mechanism of Zerumbone Release from Cross-linked Gelatin-Zeolite Y Hybrid for Oral Anticancer Drug Delivery
Norashikin Salleh,
Mohd Muzamir Mahat,
Sabrina M. Yahaya
et al.
Abstract:A hybrid of zeolite Y-gelatin film as an oral dosage form for the natural anticancer drug was achieved by homogenously incorporating the drug-loaded zeolite Y into the gelatin solution. Drug ability was analyzed using computational and experimental approaches, drug encapsulation efficiency via the BET method, and possible interactions by FTIR analyses. Zerumbone released was done in both pH 1.2 and pH 7.4 mimicking the human gastrointestinal tract conditions for 24 hrs and subjected to kinetics study via suita… Show more
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