Kinesin motors driven microtubule swarming triggered by UV light

Ishii, Satsuki; Akter, Mousumi; Murayama, Keiji; Kabir, Arif Md. Rashedul; Asanuma, Hiroyuki; Sada, Kazuki; Kakugo, Akira

doi:10.1038/s41428-022-00693-1

Cited by 5 publications

(6 citation statements)

References 34 publications

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“…Orthogonality in the context of swarm robotics is defined as a characteristic that enables different groups/types of robots to perform clustered or individual activities without interacting or interfering with each other [ 90 ]. Akira Kakugo's team targeted optical switches [ 181 ]. Previously reported examples have utilized a single optical switch alone, thus limiting further applications of swarming systems, such as the transport of different types of goods from one place to another or sorting multiple goods at the same time.…”

Section: Feature Regulation Of Collective Behaviormentioning

confidence: 99%

Collective Molecular Machines: Multidimensionality and Reconfigurability

Wang,

2024

Nano-Micro Lett.

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Molecular machines are key to cellular activity where they are involved in converting chemical and light energy into efficient mechanical work. During the last 60 years, designing molecular structures capable of generating unidirectional mechanical motion at the nanoscale has been the topic of intense research. Effective progress has been made, attributed to advances in various fields such as supramolecular chemistry, biology and nanotechnology, and informatics. However, individual molecular machines are only capable of producing nanometer work and generally have only a single functionality. In order to address these problems, collective behaviors realized by integrating several or more of these individual mechanical units in space and time have become a new paradigm. In this review, we comprehensively discuss recent developments in the collective behaviors of molecular machines. In particular, collective behavior is divided into two paradigms. One is the appropriate integration of molecular machines to efficiently amplify molecular motions and deformations to construct novel functional materials. The other is the construction of swarming modes at the supramolecular level to perform nanoscale or microscale operations. We discuss design strategies for both modes and focus on the modulation of features and properties. Subsequently, in order to address existing challenges, the idea of transferring experience gained in the field of micro/nano robotics is presented, offering prospects for future developments in the collective behavior of molecular machines.

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Section: Feature Regulation Of Collective Behaviormentioning

confidence: 99%

Collective Molecular Machines: Multidimensionality and Reconfigurability

Wang,

2024

Nano-Micro Lett.

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“…Photoswitchable ligands, such as azobenzenes and spiropyrans, can be reversibly isomerized upon exposure to a specific wavelength of light [Figure A(ii)]. The ligands can be decorated onto nonphotoresponsive agents to enable their response to light. − Swarms of cellular microtubules were generated via the use of azobenzene (Figure E). , The microtubules were labeled with photoresponsive single-stranded DNA, which was tethered with azobenzene. The DNA strands underwent association and dissociation when visible and UV light were applied, respectively [Figure E(i)].…”

Section: Optical Field-guided Micro/nanorobotic Swarmsmentioning

confidence: 99%

“…Interestingly, circular motion of the swarms occurred when flexible microtubules were applied, and a system containing swarms with flexible (circular motion) and rigid microtubules (translational motion) without crosstalk was realized because of the high selectivity of DNA-based linking. By further modifying the DNA to be photoresponsive, the swarm behavior can be tuned by using light, which has been discussed in the previous section (Photoisomerization, Figure E). , …”

Section: Chemical-guided Micro/nanorobotic Swarmsmentioning

confidence: 99%

“…228−231 Swarms of cellular microtubules were generated via the use of azobenzene (Figure 4E). 223,232 The microtubules were labeled with photoresponsive single-stranded DNA, which was tethered with azobenzene. The DNA strands underwent association and dissociation when visible and UV light were applied, respectively [Figure 4E(i)].…”

Section: Optical Field-guided Micro/nanorobotic Swarmsmentioning

confidence: 99%

“…By further modifying the DNA to be photoresponsive, the swarm behavior can be tuned by using light, which has been discussed in the previous section (Photoisomerization, Figure 4E). 223,232…”

Section: Chemical-guided Micro/nanorobotic Swarmsmentioning

confidence: 99%

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Micro/Nanorobotic Swarms: From Fundamentals to Functionalities

Law

Tang

et al. 2023

ACS Nano

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Swarms, which stem from collective behaviors among individual elements, are commonly seen in nature. Since two decades ago, scientists have been attempting to understand the principles of natural swarms and leverage them for creating artificial swarms. To date, the underlying physics; techniques for actuation, navigation, and control; fieldgeneration systems; and a research community are now in place. This Review reviews the fundamental principles and applications of micro/ nanorobotic swarms. The generation mechanisms of the emergent collective behaviors among the micro/nanoagents identified over the past two decades are elucidated. The advantages and drawbacks of different techniques, existing control systems, major challenges, and potential prospects of micro/nanorobotic swarms are discussed.

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Construction of functional microtubules and artificial motile systems based on peptide design

Inaba

2023

Polym J

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Kinesin motors driven microtubule swarming triggered by UV light

Cited by 5 publications

References 34 publications

Collective Molecular Machines: Multidimensionality and Reconfigurability

Collective Molecular Machines: Multidimensionality and Reconfigurability

Micro/Nanorobotic Swarms: From Fundamentals to Functionalities

Construction of functional microtubules and artificial motile systems based on peptide design

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