Kimura’s disease: a clinico-pathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia

Kung, I. T. M.; Gibson, James B.; Bannatyne, Patricia

doi:10.3109/00313028409067909

Cited by 200 publications

(133 citation statements)

References 12 publications

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“…However, in Kimura's disease, there is marked serum eosinophilia and hyperimmunoglobulinemia, at the cost of IgE and lymph node involvement. 4,5 In the patient of the present report, it was not possible to find serum eosinophilia or hyperimmunoglobulinemia.…”

Section: Discussionmentioning

confidence: 66%

Epithelioid hemangioma of the colon: a case report

Nonose¹,

Priolli²,

Cardinalli³

et al. 2008

Sao Paulo Med. J.

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CONTEXT: Epithelioid hemangioma or angiolymphoid hyperplasia with eosinophilia is an uncommon benign vascular neoplasm that is usually located on the face or neck. Exceptionally, it has been described affecting the colon, with only two such cases described in the worldwide literature. The aim here was to present a case of primary epithelioid hemangioma of the sigmoid colon with confirmation by immunohistochemical examination. CASE REPORT: A 37-year-old woman had had a complaint of intermittent abdominal pain for six months. Two months after the condition started, she began to present changes in her intestinal habit, with evacuations containing blood and mucus and a weight loss of 4 kg over this period. At physical examination, a palpable mass was noted in the lower left quadrant of the abdomen. Neoplasia of the colon was clinically suspected and she underwent colonoscopy. This demonstrated the presence of a vegetating sessile lesion of approximately 5 cm in diameter, at a distance of 36 cm from the anal margin. It occupied 80% of the intestinal lumen. A biopsy collected during the examination suggested a diagnosis of neoplasia of vascular origin. After surgical resection, histopathological examination of the resected specimen confirmed the diagnosis of epithelioid hemangioma of the colon, which was backed up by the immunohistochemical panel (factor VIII, Ki-67, CD-34). At present, three years after the surgery, the patient is asymptomatic, she has recovered her normal weight and she has normal findings from control colonoscopy. Despite the rarity of neoplasia of vascular origin, this possibility should be considered in the differential diagnosis for colorectal tumors.

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Section: Discussionmentioning

confidence: 66%

Epithelioid hemangioma of the colon: a case report

Nonose¹,

Priolli²,

Cardinalli³

et al. 2008

Sao Paulo Med. J.

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“…16 Kimura's disease should be histopathologically differentiated from the following diseases: angiolymphoid hyperplasia with eos inophilia (ALHE), Hodgkin lymphoma, angioimmunoblastic T-cell lymphoma, Langerhans cell histiocytosis, florid follicular hyperplasia, Castleman disease, dermatopathic lymphadenopathy, allergic granulomatosis, parasitic lymphadenitis and drug reaction. [17][18][19] ALHE is the most easily confused for Kimura's disease which is now considered to be a kind of endothelial neoplasm related to inflammatory stimulation. ALHE often affects middle-aged women who typically present with a superficial mass.…”

Section: Discussionmentioning

confidence: 99%

Kimura’s Disease: A case series with literature review

Hemalata¹,

Suguna²

2014

Int Jour of Biomed Res

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“…KD is usually seen in young adults. A series by Kung et al reported a median age of 28 years [10]. In Kimura's disease there is classically a dense inflammatory infiltrate characterized by proliferating lymphoid tissue with germinal centres, eosinophilic microabscesses and fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Kimura’s disease – a rare entity

Talwar¹,

Puri²

2013

Our Dermatol Online

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Introduction: Kimura's disease is a benign, but locally injurious disease with a marked predilection for the head and neck. Case Report: We present two cases of this rare disease. Discussion: Of uncertain aetiology, its tendency to present as a discrete, enlarging mass with associated lymphadenopathy makes it a condition of interest to clinicians who see head and neck pathology. Although rare, there are increasing numbers of reports of the condition and it should become part of the standard differential diagnosis.

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Kimura’s disease: a clinico-pathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia

Cited by 200 publications

References 12 publications

Epithelioid hemangioma of the colon: a case report

Epithelioid hemangioma of the colon: a case report

Kimura’s Disease: A case series with literature review

Kimura’s disease – a rare entity

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