Kielbone in New Attachment Attempts in Humans

Abstract

The purpose of this investigation was to evaluate, in humans, the use of Kielbone as a substitute for fresh autogenous bone in treating periodontal intrabony defects. A total of 92 intrabony defects were treated with a previously described new attachment procedure utilizing free mucosal grafts to cover the intrabony defects following bone grafting. Kielbone was placed in 46 of these defects, while the remaining 46 defects were treated with autogenous bone grafts. The results were evaluated after 6 months by periodontal probing and assessment of the bone level as seen on periodical, identical radiographs. No differences were observed between the amount of clinical gain of attachment obtained in defects treated with Kielbone and those treated with autogenous jaw bone. This indicates that in surgical procedures attempting to restore lost connective tissue attachment, Kielbone constitutes a suitable replacement for fresh autogenous bone. The results are discussed in th light of recent studies that challenge the beneficial effect of bone grafts in the treatment of intrabony defects.

Regeneration and repair of periodontal tissues

“…It is well known that the surgical removal of the junctional epithelium, or repeated postoperative epithelial curettage, is inefficient (76)(77)(78). Also, other attempts at surgical manipulation for the purpose of delaying the apical migration of the oral epithelium do not seem to have given clinical success beyond that of conventional flap management (63,(79)(80)(81)(82).…”

A comparative study on the use of a HA/collagen/chondroitin sulphate biomaterial (Biostite®) and a bovine‐derived HA xenograft (Bio‐Oss®) in the treatment of deep intra‐osseous defects

“…Clinical (Scopp et al 1966, Older 1967) and histological (Arrocha et al 1968, Nielsen et al 1980, 1981 studies promoted the use of anorganic bovine bone for grafting in intra-osseous defects. In this context, an anorganic xenograft (Bio-Oss s , Geistlich Pharma AG, Wolhusen, Switzerland) was developed for bone regeneration procedures.…”

The Use of Periograf® in Periodontal Defects

“…In the quest to restore lost attachment, a variety of implant materials have been investigated.12 Numerous studies have shown varying degrees of success through the implantation of different forms of bone.3 8 Furthermore, in a study by Caton et al,14 no new connective tissue attachment was seen microscopically when a variety of implanted materials were placed in periodontal defects in rhesus monkeys. A junctional epithelium was always interposed between the new bone and the root surface.…”