Kidney support for babies: building a comprehensive and integrated neonatal kidney support therapy program

Mohamed, Tahagod; Morgan, Jolyn; Askenazi, David; Menon, Shina

doi:10.1007/s00467-022-05768-y

Cited by 5 publications

(1 citation statement)

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“…The possibility to integrate more KRT options for small children increases the demand for resources and will require adequate training and established protocols and procedures. A recent educational review provides detailed recommendations on how to build a comprehensive and integrated neonatal kidney support therapy program in those countries where technologies and resources are available [46].…”

Section: Aftermath Of the Scientific Revolutionmentioning

confidence: 99%

New perspectives in pediatric dialysis technologies: the case for neonates and infants with acute kidney injury

2023

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Advancements in pediatric dialysis generally rely on adaptation of technology originally developed for adults. However, in the last decade, particular attention has been paid to neonatal extracorporeal therapies for acute kidney care, an area in which technology has made giant strides in recent years. Peritoneal dialysis (PD) is the kidney replacement therapy (KRT) of choice in the youngest age group because of its simplicity and effectiveness. However, extracorporeal blood purification provides more rapid clearance of solutes and faster fluid removal. Hemodialysis (HD) and continuous KRT (CKRT) are thus the most used dialysis modalities for pediatric acute kidney injury (AKI) in developed countries. The utilization of extracorporeal dialysis for small children is associated with a series of clinical and technical challenges which have discouraged the use of CKRT in this population. The revolution in the management of AKI in newborns has started recently with the development of new CKRT machines for small infants. These new devices have a small extracorporeal volume that potentially prevents the use of blood to prime lines and dialyzer, allow a better volume control and the use of small-sized catheter without compromising the blood flow amount. Thanks to the development of new dedicated devices, we are currently dealing with a true “scientific revolution” in the management of neonates and infants who require an acute kidney support.

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Section: Aftermath Of the Scientific Revolutionmentioning

confidence: 99%