Kidney retrieval after sudden out of hospital refractory cardiac arrest: a cohort of uncontrolled non heart beating donors

Fieux, Fabienne; Losser, Marie Reine; Bourgeois, E.; Bonnet, F.; Marie, Olivier; Gaudez, F.; Abboud, Imad; Donay, Jean Luc; Mourey, F; Adnet, Frédéric; Jacob, Laurent

doi:10.1186/cc8022

Cited by 81 publications

(73 citation statements)

References 32 publications

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“…Non-heart beating organ donation programmes have been developed in an attempt to increase the donor pool for organ transplantation [49]. Following confirmation of cardiac death (in accordance with local guidelines/laws) patients may be eligible for non-heart beating organ donation.…”

Section: Transplantationmentioning

confidence: 99%

Mechanical chest-compression devices: current and future roles

Perkins

Brace

Gates

2010

Current Opinion in Critical Care

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Purpose of review:It is recognised that the quality of CPR is an important predictor of outcome from cardiac arrest yet studies consistently demonstrate that the quality of CPR performed in real life is frequently sub-optimal. Mechanical chest compression devices provide an alternative to manual CPR. This review will consider the evidence and current indications for the use of these devices. Recent findings:Physiological and animal data suggest that mechanical chest compression devices are more effective than manual CPR. However there is no high quality evidence showing improved outcomes in humans. There are specific circumstances where it may not be possible to perform manual CPR effectively e.g. during ambulance transport to hospital, en-route to and during cardiac catheterisation, prior to organ donation and during diagnostic imaging where using these devices may be advantageous. Summary:There is insufficient evidence to recommend the routine use of mechanical chest compression devices. There may be specific circumstances when CPR is difficult or impossible where

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Section: Transplantationmentioning

confidence: 99%

Mechanical chest-compression devices: current and future roles

Perkins

Brace

Gates

2010

Current Opinion in Critical Care

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“…A group in Paris has recently implemented a similar protocol and identified 27 donors over a 17-month period. 8 It is possible that other groups have instituted similar protocols, but have not published their experiences.…”

Section: Experiences With Dcd Involving the Ed And Emsmentioning

confidence: 99%

“…Several European health care systems have implemented protocols to allow DCD in both of these settings, and some U.S. cities have piloted similar protocols. [4][5][6][7][8] Although emergency physicians (EPs) will likely have little involvement with inpatient DCD protocols and cases, these extended protocols directly involve EPs. Indeed, EPs will likely lead the way in implementing these protocols and even determining how widespread and accepted they are.…”

mentioning

confidence: 99%

Donation After Cardiac Death and the Emergency Department: Ethical Issues

Simon

Schears

Padela

2014

Academic Emergency Medicine

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“…The relatively unknown ischemic injury and the unplanned situation of the procedure have led to a general reluctance to initiate uncontrolled DCD programs and to accept uncontrolled DCD kidneys for transplantation. There are a limited number of uncontrolled DCD kidney transplantation programs in Spain and France with excellent results [4,5]. Furthermore, a recent study shows that the clinical outcome of uncontrolled DCD kidneys is comparable to that of controlled DCD kidneys [6].…”

Section: Introductionmentioning

confidence: 99%

Kidneys from uncontrolled donors after cardiac death: which kidneys do worse?

et al. 2013

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SummaryKidneys from uncontrolled donors after cardiac death (DCD) expand the donor pool, but are associated with more primary nonfunction (PNF) and delayed graft function (DGF) compared with more conventional donor kidneys. It remains unclear, which factors influence outcome of uncontrolled donation. Therefore, we studied which donor, graft, and recipient characteristics are associated with PNF in a large cohort study. The association between different characteristics and short-term graft function was analyzed for kidneys procured in the Maastricht region from 1 January 1981 to 1 July 2009. Patients were followed until 7 January 2010. A total of 135 uncontrolled donor kidneys were included in this study. The incidence of PNF and DGF was 22% and 61%, respectively. Increasing donor age is an independent risk factor for graft failure in a univariate analysis (OR 1.035, 95% CI 1.004-1.068, P = 0.028). Donor age remains strongly associated with PNF in a multivariate analysis (OR 1.064, 95% CI 1.013-1.118, P = 0.014). However, the predictive value of donor age alone is poor (AURC 0.640, 95% CI 0.553-0.721). Increasing donor age of uncontrolled DCD donors is a major risk factor for PNF. Other clinically relevant variables were not associated with PNF. Donor age is strongly associated with PNF and remains an important parameter in donor selection.

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Kidney retrieval after sudden out of hospital refractory cardiac arrest: a cohort of uncontrolled non heart beating donors

Cited by 81 publications

References 32 publications

Mechanical chest-compression devices: current and future roles

Mechanical chest-compression devices: current and future roles

Donation After Cardiac Death and the Emergency Department: Ethical Issues

Kidneys from uncontrolled donors after cardiac death: which kidneys do worse?

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