Kidney pathology and parasite intensity in rainbow trout Oncorhynchus mykiss surviving proliferative kidney disease: time course and influence of temperature

Schmidt‐Posthaus, Heike; Bettge, Kathrin; Förster, Ursula; Segner, Helmut; Wahli, Thomas

doi:10.3354/dao02417

Cited by 51 publications

(71 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, comparable to our results gained from experimental studies, PKD prevalence and the composition of pathological lesions in infected YOY were not associated with water temperature. It has previously been shown that rainbow trout surviving the clinical phase of PKD are able to completely regenerate renal morphology and that this process is not influenced by water temperature (Ferguson 1981, Kent & Hedrick 1985, Clifton-Hadley et al 1987, Schmidt-Posthaus et al 2012. In accordance with these findings, in our study fish from all tributaries, independent of summer-warm or summercool water, renal morphology could be completely restored during the winter months.…”

Section: Discussionsupporting

confidence: 81%

“…Therefore, translocation in the tubular lumen was obvious, but spore elimination until spring was only seen in the summer-cool tributaries. In a recent experimental study dealing with rainbow trout, we showed that as soon as 103 d post-infection no T. bryosalmonae were visible by IHC, independent of water temperature (Schmidt-Posthaus et al 2012). However, translocation into the tubular lumen was not obvious in the latter study, as elimination of T. bryo salmonae seemed rather to be taking place through degeneration of the parasites in the interstitium than by translocation into the tubular lumen (Bettge et al 2009, Schmidt-Posthaus et al 2012.…”

Section: Discussionmentioning

confidence: 75%

“…We have shown in previous experimental studies that PKD prevalence and the associated pathology is only slightly influenced by water temperature in rainbow trout YOY (Schmidt-Posthaus et al 2012). In the present study, we investigated the influence of water temperature on the disease under natural conditions in brown trout Salmo trutta fario.…”

Section: Discussionmentioning

confidence: 99%

“…In a recent experimental study dealing with rainbow trout, we showed that as soon as 103 d post-infection no T. bryosalmonae were visible by IHC, independent of water temperature (Schmidt-Posthaus et al 2012). However, translocation into the tubular lumen was not obvious in the latter study, as elimination of T. bryo salmonae seemed rather to be taking place through degeneration of the parasites in the interstitium than by translocation into the tubular lumen (Bettge et al 2009, Schmidt-Posthaus et al 2012. These species differences were also shown by Morris & Adams (2006) and Grabner & El-Matbouli (2008), who were only able to demonstrate excreted spores in brown Salmo trutta and brook trout Salvelinus fontinalis, but not in rainbow trout.…”

Section: Discussionmentioning

confidence: 99%

“…In young-of-the-year (YOY), proliferative and granulomatous nephritis and necrotizing vasculitis with thrombus formation are host reactions to parasite infestation (Hedrick et al 1993, El-Matbouli & Hoffmann 1994, Bettge et al 2009). In laboratory studies, we pre viously showed that surviving fish can recover with complete regeneration of renal morphology (Schmidt-Posthaus et al 2012). After complete re generation, no T. bryosalmonae spores were de tected in surviving rainbow trout by histology or immunohistochemistry (SchmidtPosthaus et al 2012).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Complex interaction between proliferative kidney disease, water temperature and concurrent nematode infection in brown trout

Schmidt‐Posthaus¹,

Steiner²,

Müller³

et al. 2013

Dis. Aquat. Org.

Self Cite

View full text Add to dashboard Cite

Proliferative kidney disease (PKD) is a temperature-dependent disease caused by the myxozoan Tetracapsuloides bryosalmonae. It is an emerging threat to wild brown trout Salmo trutta fario populations in Switzerland. Here we examined (1) how PKD prevalence and pathology in young-of-the-year (YOY) brown trout relate to water temperature, (2) whether wild brown trout can completely recover from T. bryosalmonae-induced renal lesions and eliminate T. bryosalmonae over the winter months, and (3) whether this rate and/or extent of the recovery is influenced by concurrent infection. A longitudinal field study on a wild brown trout cohort was conducted over 16 mo. YOY and age 1+ fish were sampled from 7 different field sites with various temperature regimes, and monitored for infection with T. bryosalmonae and the nematode Raphidascaris acus. T. bryosamonae was detectable in brown trout YOY from all sampling sites, with similar renal pathology, independent of water temperature. During winter months, recovery was mainly influenced by the presence or absence of concurrent infection with R. acus larvae. While brown trout without R. acus regenerated completely, concurrently infected brown trout showed incomplete recovery, with chronic renal lesions and incomplete translocation of T. bryosalmonae from the renal interstitium into the tubular lumen. Water temperature seemed to influence complete excretion of T. bryosalmonae, with spores remaining in trout from summer-warm rivers, but absent in trout from summer-cool rivers. In the following summer months, we found PKD infections in 1+ brown trout from all investigated river sites. The pathological lesions indicated a reinfection rather than a proliferation of remaining T. bryosalmonae. However, disease prevalence in 1+ trout was lower than in YOY.

show abstract

Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Complex interaction between proliferative kidney disease, water temperature and concurrent nematode infection in brown trout

Schmidt‐Posthaus¹,

Steiner²,

Müller³

et al. 2013

Dis. Aquat. Org.

Self Cite

View full text Add to dashboard Cite

show abstract

Exploration of the 2016 Yellowstone River fish kill and proliferative kidney disease in wild fish populations

et al. 2021

View full text Add to dashboard Cite

Proliferative kidney disease (PKD) is an emerging disease that recently resulted in a large mortality event of salmonids in the Yellowstone River (Montana, USA). Total PKD fish mortalities in the Yellowstone River were estimated in the tens of thousands, which resulted in a multi-week river closure and an estimated economic loss of US$500,000. This event shocked scientists, managers, and the public, as this was the first occurrence of the disease in the Yellowstone River, the only reported occurrence of the disease in Montana in the past 25 yr, and arguably the largest wild PKD fish kill in the world. To understand why the Yellowstone River fish kill occurred, we used molecular and historical data to evaluate evidence for several hypotheses: Was the causative parasite Tetracapsuloides bryosalmonae a novel invader, was the fish kill associated with a unique parasite strain, and/or was the outbreak caused by unprecedented environmental conditions? We found that T. bryosalmonae is widely distributed in Montana and have documented occurrence of this parasite in archived fish collected in the Yellowstone River prior to the fish kill. T. bryosalmonae had minimal phylogeographic population structure, as the DNA of parasites sampled from the Yellowstone River and distant water bodies were very similar. These results suggest that T. bryosalmonae could be endemic in Montana. Due to data limitations, we could not reject the hypothesis that the fish kill was caused by a novel and more virulent genetic strain of the parasite. Finally, we found that single-year environmental conditions are insufficient to explain the cause of the 2016 Yellowstone River PKD outbreak. Other regional rivers where we documented T. bryosalmonae had similar or even more extreme conditions than the Yellowstone River and similar or more extreme conditions have occurred in the Yellowstone River in the recent past, yet mass PKD mortalities have not been documented in either instance. We conclude by placing these results and unresolved hypotheses into the broader context of international research on T. bryosalmonae and PKD, which strongly suggests that a better understanding of bryozoans, the primary host of T. bryosalmonae, is required for better ecosystem understanding.

show abstract

Fish Immune Responses to Myxozoa

Sitjà‐Bobadilla

Schmidt‐Posthaus

Wahli

et al. 2015

Myxozoan Evolution, Ecology and Development

View full text Add to dashboard Cite

Kidney pathology and parasite intensity in rainbow trout Oncorhynchus mykiss surviving proliferative kidney disease: time course and influence of temperature

Cited by 51 publications

References 30 publications

Complex interaction between proliferative kidney disease, water temperature and concurrent nematode infection in brown trout

Complex interaction between proliferative kidney disease, water temperature and concurrent nematode infection in brown trout

Exploration of the 2016 Yellowstone River fish kill and proliferative kidney disease in wild fish populations

Fish Immune Responses to Myxozoa

Contact Info

Product

Resources

About