Kidney Dysfunction in Critically Ill Patients

Polushin, Yu. S.; Соколов, Д. В.

doi:10.21292/2078-5658-2018-15-5-54-64

Cited by 8 publications

(1 citation statement)

References 42 publications

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“…Клиническое значение выделения острой болезни почек состоит в том, что это позволило не только сделать концепцию патологического континуума повреждения почек завершенной, но и сконцентрировать внимание специалистов на более активном применении лечебных технологий с целью улучшения прогноза дисфункции. В частности, для определения траектории течения острой болезни почек и индивидуализированной оценки рисков рецидивов ОПП необходим динамический контроль биомаркеров повреждения почек, трендов СКФ и данных визуализирующих методик, например ультразвукового исследования почек [24].…”

Section: определение острого повреждения почек группой экспертов Kdigounclassified

Acute kidney injury in cardiac surgery: definition, epidemiology, outcomes and socio-economic significance

Каменщиков¹,

Podoksenov²,

Diakova³

et al. 2020

PKiK

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Surgical intervention on an ‘open’ heart during cardio-pulmonary bypass is the method of choice for patients with valvular defects, complicated forms of coronary heart disease and combined pathology. The level of perioperative mortality in these interventions range from 2 % to 10 %. Acute kidney injury associated with cardiac surgery is a common and serious complication which dramatically worsens operative prognoses and results. According to several major studies, the incidence of acute renal injury in cardiac surgery is comparable with the incidence of myocardial infarction, with corresponding unsatisfactory outcomes. The introduction of the term ‘acute kidney injury’ into clinical practise, replacing the concept of acute renal failure, occurred relatively recently. This facilitated a universal definition for this condition, and unified the criteria for diagnosis and stratification of acute renal dysfunction severity. The article defines acute kidney injury using RIFLE, AKIN and KDIGO criteria. Acute kidney injury in cardiac surgery dramatically worsens short-term results and long-term outcomes, and thus increases the economic cost of treating patients. According to some reports, in industrialised countries, the health costs associated with acute kidney injury are estimated at $ 1 billion. Acute kidney injury is associated with approximately 300,000 deaths per annum, as well as approximately 300,000 new cases of chronic kidney disease. Cumulative expenses associated with acute renal injury in cardiac surgery are not directly limited to the hospitalisation period, but are often prolonged and/or deferred. These patients require additional financial expenses after discharge from hospital, which once again exemplifies this problem in cardiac surgery. Manifest acute kidney injury in the postoperative period of cardiac surgery leads to an increased number of extrarenal complications, reduced short-and long-term survival rates, increased economic costs in hospitals and prolonged treatment effects in the long-term. The introduction of a single definition of cardiac acute renal injury according to KDIGO criteria into clinical practise will identify patient groups with a high risk of developing this pathology. Similarly, it will also facilitate timely measures to prevent the development of complications in postoperative periods, which will reduce the risk of complications in cardiac patients.Received 10 July 2020. Revised 2 September 2020. Accepted 9 September 2020.Funding: The study did not have sponsorship.Conflict of interest: Authors declare no conflict of interest.Author contributions Conception and design: N.O. Kamenshchikov, Y.K. Podoksenov, M.L. Diakova Data collection and analysis: N.O. Kamenshchikov, A.M. Boyko, M.L. Diakova Drafting the article: N.O. Kamenshchikov, M.L. Diakova, A.M. Boyko Critical revision of the article: M.L. Diakova, Y.K. Podoksenov Final approval of the version to be published: N.O. Kamenshchikov, Y.K. Podoksenov, M.L. Diakova, A.M. Boyko, B.N. Kozlov

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Section: определение острого повреждения почек группой экспертов Kdigounclassified

Acute kidney injury in cardiac surgery: definition, epidemiology, outcomes and socio-economic significance

Каменщиков¹,

Podoksenov²,

Diakova³

et al. 2020

PKiK

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Occurrence and correlates of azotaemia in dogs presented for veterinary care in a tertiary veterinary hospital in Nigeria

Emejuo,

Omeke,

Ihedioba

et al. 2023

Rev. Med. Vet.

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This study evaluated the occurrence of azotemia and the relationship between azotemia, breed, sex, and age in dogs brought for veterinary treatment at a tertiary veterinary hospital in Eastern Nigeria. A total of 304 dogs of varied breeds and ages comprising males and females were evaluated in this study. Renal dysfunction was assessed by evaluation of serum creatinine levels using the International Renal Interest Society criterion for diagnosis of renal dysfunction, a cut-off serum creatinine value of ≥ 1.4 mg/dl was used to classify the dogs as positive for azotemia or not. Results of the study showed that 34 (11.2%) dogs in the sample had azotemia. There were significant variations (p < 0.05) in the occurrence of azotemia among breeds, with Caucasians having the highest occurrence (5.9%), followed by Mastiffs (2.6%), Mongrels (2.0%), and Alsatians (0.7%). The occurrence of azotemia was significantly higher (p < 0.05) in females than in males. There was significant variation (p < 0.05) in the occurrence of azotemia among the different age groups, with young dogs having a higher occurrence than puppies and adults.

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The Russian anesthesiology and resuscitation in 2019–2020

Полушин

2020

Vestn. anesteziol. reanimatol.

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Отечественная анестезиология-реаниматология в 2019-2020 гг. Ю. С. ПОЛУШИН ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет им. ак. И. П. Павлова» МЗ РФ, Санкт-Петербург, РФ Редакционная статья рассматривает итоги и тенденции развития анестезиолого-реаниматологического направления в стране после прошедшего в прошлом году 2-го Конгресса «Актуальные вопросы медицины критических состояний». Особое внимание уделено практической реализации концепций ускоренного выздоровления пациента и периоперационной медицины, а также острого повреждения почек. Отмечено, что изменение концептуальных представлений о дисфункции почек заставляет переосмыслить принципы ведения больных в критическом состоянии, обращая внимание на факторы, способные вызывать (усугублять) повреждение почек. Акцентировано внимание на том, что механистическое внедрение в практику любых новых методик без оглядки на последствия может приносить не только пользу, но и вред. Подчеркнуто, что лишь предупреждение роста когорты больных с хронической болезнью почек и грамотное своевременное применение современных диализных технологий способны обеспечить снижение государственных затрат на гемодиализ после выписки больных из стационара. Показана эффективность междисциплинарного взаимодействия различных профессиональных сообществ в случае совместного поиска решений на примере разработки проблемы антибиотикорезистентности.

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Kidney Dysfunction in Critically Ill Patients

Cited by 8 publications

References 42 publications

Acute kidney injury in cardiac surgery: definition, epidemiology, outcomes and socio-economic significance

Acute kidney injury in cardiac surgery: definition, epidemiology, outcomes and socio-economic significance

Occurrence and correlates of azotaemia in dogs presented for veterinary care in a tertiary veterinary hospital in Nigeria

The Russian anesthesiology and resuscitation in 2019–2020

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