Ki-67 is expressed in multiplying forms of Schistosoma mansoni, but not in snail host tissues

Abstract

Ki-67 is a protein expressed in the nucleus of several species during cell-division, being absent during the GO resting phase of the cellular cycle. During attempts to disclose mitosis in the so-called "amebocyte-producing organ" in Biomphalaria glabrata infected with Schistosoma mansoni, the parasite multiplying forms appeared strongly marked for Ki-67, while the snail tissues were completely negative. These data are worth registering to complement general data on Ki-67, and to help future studies on the relationship of the parasite and of its intermediate host.

Ki-67 and the Chromosome Periphery Compartment in Mitosis

“…Xenopus laevis [76] and even Schizosaccharomyces pombe [77], Ki-67 is apparently only conserved in vertebrates, and even in vertebrates, the primary structure of the protein is remarkably variable. In the sole exception to this, Ki-67 has been reported in the dividing cells of Schistosoma mansoni [78].…”