Ki-67 and CDK1 Control the Dynamic Association of Nuclear Lipids with Mitotic Chromosomes
Hsiao-Tang Hu,
Ueh-Ting Tim Wang,
Bi-Chang Chen
et al.
Abstract:A hallmark of eukaryotic species is having distinct numbers of chromosomes surrounded by a nuclear envelope to separate nuclear transcription and RNA processing from cytosolic translation. In animal and plant cells undergoing open mitosis, the nuclear envelope disintegrates before the chromosomes divide into two daughter cells. To ensure faithful genome inheritance, chromosome individualization is involved in partitioning the fully condensed sister chromatids during mitosis. Ki67, a surfactant-like protein tha… Show more
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