Key Steps in Conducting Systematic Reviews for Underpinning Clinical Practice Guidelines: Methodology of the European Association of Urology

Knoll, Thomas; Omar, Muhammad Imran; MacLennan, Steven; Hernández, Virginia; Canfield, Steven E.; Yuan, Yuhong; Bruins, Max; Marconi, Lorenzo; Poppel, Hein Van; N’Dow, James; Sylvester, Richard

doi:10.1016/j.eururo.2017.08.016

Cited by 156 publications

(76 citation statements)

References 32 publications

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“…Despite this report represents the first systematic review on alpha‐blockers for the treatment of MS‐related NLUTD, several limitations should be addressed. The Cochrane Handbook and the EAU Guidelines Office recommend avoiding pooled analyzes when there are less than two randomized trials available which were the case in the present study . The reason why we provide the results of a meta‐analysis is twofold: first and foremost, it allows discussing the direction (not the magnitude) of efficacy and the variability of effects across studies.…”

Section: Discussionmentioning

confidence: 99%

Alpha‐blockers for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta‐analysis. A report from the Neuro‐Urology Promotion Committee of the International Continence Society (ICS)

Schneider

Tornic

Sýkora

et al. 2019

Neurourology and Urodynamics

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Aim We aimed to systematically assess the evidence on the efficacy and safety of alpha‐blockers in patients with multiple sclerosis (MS) suffering from neurogenic lower urinary tract dysfunction (NLUTD). Methods The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement was used to perform this systematic review. An electronic search of Cochrane register, Embase, Medline, Scopus (last search 3 March 2018) and screening of reference lists as well as reviews were used to identify the studies. Articles were included if they reported on efficacy/safety of alpha‐blockers for the treatment of NLUTD in patients with MS. Results After screening of 7′015 abstracts, three studies enrolling a total of 50 patients were included: one randomized, placebo‐controlled, single‐blind trial and two prospective cohort studies. Alpha‐blocker treatment was successful in 50% to 96% of the patients. Pooling data from the three included studies, the relative risk for successful alpha‐blocker treatment was 3.89 (95% confidence interval 2.7‐7.0). The general safety profile of alpha‐blockers was favorable with 8% of the patients reporting adverse events. Conclusions Alpha‐blockers may be effective and safe for treating NLUTD in female and male patients with MS but the studies were small and the overall quality of evidence was low. To make definitive conclusions, well designed randomized controlled trials are highly warranted.

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Section: Discussionmentioning

confidence: 99%

Alpha‐blockers for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta‐analysis. A report from the Neuro‐Urology Promotion Committee of the International Continence Society (ICS)

Schneider

Tornic

Sýkora

et al. 2019

Neurourology and Urodynamics

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“…Five steps exist in systematic review. First, the researcher frames the research question(s) for review (Khan et al, 2003;Knoll et al, 2017). For this study, the research question is this: What processes and strategies are available to restaurant leaders to reduce food waste costs?…”

Section: Methodsological Approachmentioning

confidence: 99%

“…Key terms were identified by a review of the literature. The second step is to find relevant studies (Khan et al, 2003;Knoll et al, 2017). For this study, academic resources were accessed from (a) EBSCOhost, (b) ProQuest, (c) ScienceDirect, (d) Academic Search, (e) ABI/INFORM, (f) Emerald, (g) Springer, (h) SAGE Journals, (i) John Wiley and Sons, and (j) Taylor and Francis.…”

Section: Methodsological Approachmentioning

confidence: 99%

“…The third step is to assess the quality of the studies (Khan et al, 2003;Knoll et al, 2017). Journals used in this article were assessed under the assumption the peer-review process is a reliable indicator that the literature review, research methods, threats to validity, and the accuracy of reporting of findings/results were addressed and are acceptable by a thorough examination of at least two independent experts in the same field.…”

Section: Methodsological Approachmentioning

confidence: 99%

“…The fourth step is to summarize the evidence (Khan et al, 2003;Knoll et al, 2017). Evidence was derived from the extant literature.…”

Section: Methodsological Approachmentioning

confidence: 99%

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Ways to Reduce Restaurant Industry Food Waste Costs

Blum

2020

IJAMT

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Food waste costs U.S. restaurant leaders billions of dollars per year. The purpose of this research was to provide restaurant leaders with processes and strategies to reduce food waste costs. The research method used was systematic literature review in addressing this research question: What processes and strategies are available to U.S. restaurant leaders to reduce food waste costs? This study addresses a gap in literature related to processes and strategies to reduce food waste costs. Six processes and seven strategies to reduce food waste costs were presented.

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Selection of patients for nerve sparing surgery in robot‐assisted radical prostatectomy

et al. 2021

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Context Robot‐assisted radical prostatectomy (RARP) has become the standard surgical procedure for localized prostate‐cancer (PCa). Nerve‐sparing surgery (NSS) during RARP has been associated with improved erectile function and continence rates after surgery. However, it remains unclear what are the most appropriate indications for NSS. Objective The objective of this study is to systematically review the available parameters for selection of patients for NSS. The weight of different clinical variables, multiparametric magnetic‐resonance‐imaging (mpMRI) findings, and the impact of multiparametric‐nomograms in the decision‐making process on (side‐specific) NSS were assessed. Evidence acquisition This systematic review searched relevant databases and included studies performed from January 2000 until December 2020 and recruited a total of 15 840 PCa patients. Studies were assessed that defined criteria for (side‐specific) NSS and associated them with oncological safety and/or functional outcomes. Risk of bias assessment was performed. Evidence synthesis Nineteen articles were eligible for full‐text review. NSS is primarily recommended in men with adequate erectile function, and with low‐risk of extracapsular extension (ECE) on the side‐of NSS. Separate clinical and radiological variables have low accuracy for predicting ECE, whereas nomograms optimize the risk‐stratification and decision‐making process to perform or to refrain from NSS when oncological safety (organ‐confined disease, PSM rates) and functional outcomes (erectile function and continence rates) were assessed. Conclusions Consensus exists that patients who are at high risk of ECE should refrain from NSS. Several multiparametric preoperative nomograms were developed to predict ECE with increased accuracy compared with single clinical, pathological, or radiological variables, but controversy exists on risk thresholds and decision rules on a conservative versus a less‐conservative surgical approach. An individual clinical judgment on the possibilities of NSS set against the risks of ECE is warranted. Patient summary NSS is aimed at sparing the nerves responsible for erection. NSS may lead to unfavorable tumor control if the risk of capsule penetration is high. Nomograms predicting extraprostatic tumor‐growth are probably most helpful.

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Key Steps in Conducting Systematic Reviews for Underpinning Clinical Practice Guidelines: Methodology of the European Association of Urology

Abstract: Clinical practice guidelines should be evidence based, and systematic reviews and meta-analyses are essential in their production. We have discussed the key steps of conducting systematic reviews and meta-analyses in this paper.

Cited by 156 publications

References 32 publications

Alpha‐blockers for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta‐analysis. A report from the Neuro‐Urology Promotion Committee of the International Continence Society (ICS)

Alpha‐blockers for treating neurogenic lower urinary tract dysfunction in patients with multiple sclerosis: A systematic review and meta‐analysis. A report from the Neuro‐Urology Promotion Committee of the International Continence Society (ICS)

Ways to Reduce Restaurant Industry Food Waste Costs

Selection of patients for nerve sparing surgery in robot‐assisted radical prostatectomy

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