Ketamine Induction in Poor-Risk Patients

Nettles, D.; HERRIN, THOMAS J.; Mullen, Jesse G.

doi:10.1097/00132586-197310000-00030

Cited by 7 publications

(3 citation statements)

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“…The quite complex causes of both anesthetic complications and mortality where multiple factors are involved and the preexisting clinical disease or organ dysfunction is an important factor in morbidity and mortality [23]. ketamine is advocated to anesthetize high risk cardiac patient as ketamine does not cause profound cardiovascular depression [24]. The limited use of ketamine as a sole anesthetic could be attributed to muscle hypertonicity, myoclonus, violent recovery and occasionally convulsions [25].…”

Section: Discussionmentioning

confidence: 99%

Overdosage of Ketamine Anaesthetic Agent in Cats with Special Reference to Clinical Assessment

Ali,

Alhyani,

Thanoon

2024

Egyptian Journal of Veterinary Sciences

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T HIS study aimed to evaluate clinically the anasthetic overdosage of ketamine in cats. 10 local adult cats from both sexes were used to conduct this study. High dose of ketamine (150 mg/kg) was administered intramuscularly in all cats. Measurement of heart rate and respiratory rate as well as checking of certain reflexes were performed at regular intervals for 6 hours. Sedation, analgesia and muscle relaxation were evaluated depending on certain scores. Critical levels or clinical signs of cyanosis were not observed following administration of this high dose of ketamine which was confirmed by the measured values. Deaths of the anesthetized cats were not reported due to ketamine overdosage. High extension of the recovery period was only the main noticed result of the increased dose level of ketamine without any improvement in the anesthetic effect of this drug. Excellent sedation, profound analgesia and moderated muscle relaxation were reported in almost all anesthetized cats. In conclusion, clinical signs of acute toxicity were not reported and severe misjudgments of the bodyweight resulting in high dose of ketamine or even accidental administration increased dose level would not result into fatal outcomes.

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Section: Discussionmentioning

confidence: 99%

Overdosage of Ketamine Anaesthetic Agent in Cats with Special Reference to Clinical Assessment

Ali,

Alhyani,

Thanoon

2024

Egyptian Journal of Veterinary Sciences

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“…10,37 This has led to many reported cases in anesthetic management of patients with reactive airway disease. 38 –41 Beyond that, it has favorable effects clinically on systemic hemodynamics. 12,39 Unlike many of the agents discussed above, ketamine has not been shown to decrease systolic, diastolic, or mean arterial pressure in normotensive patients and, in many instances, may increase these variables.…”

Section: Discussionmentioning

confidence: 99%

The Future of Intensive Care Unit Sedation: A Report of Continuous Infusion Ketamine as an Alternative Sedative Agent

Benken

Goncharenko

2016

Journal of Pharmacy Practice

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This report describes a patient case utilizing a nontraditional sedative, continuous infusion ketamine, as an alternative agent for intensive care unit (ICU) sedation. A 27-year-old female presented for neurosurgical management of a coup contrecoup injury, left temporal fracture, epidural hemorrhage (EDH), and temporal contusion leading to sustained mechanical ventilation. The patient experienced profound agitation during mechanical ventilation and developed adverse effects with all traditional sedatives: benzodiazepines, dexmedetomidine, opioids, and propofol. Ketamine was titrated to effect and eliminated the need for other agents. This led to successful ventilator weaning, extubation, and transition of care. Given the unique side effect profile of ketamine, it is imperative that information is disseminated on potential utilization of this agent. More information is needed regarding dosing, monitoring, and long-term effects of utilizing ketamine as a continuous ICU sedative, but given the analgesia, anesthesia, and cardiopulmonary stability, future utilization of this medication for this indication seems promising.

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“…induction agents available were thiopental and ketamine. Ketamine proved to be a particularly useful agent for induction of draw-over anesthesia (12). When administered slowly, it did not cause respiratory depression.…”

Section: Triagementioning

confidence: 98%

The Falkland Islands Campaign Resuscitation and Anesthesia in a Battle Situation

Jowitt

1985

J. World Assoc. Emerg. Disaster Med.

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During the early summer of 1982, Her Majesty's Armed Forces embarked upon an operation to repossess the Falkland Islands. The campaign was fought over a difficult terrain and under hostile climatic conditions, 8,000 miles from home shores. Resupply was difficult, sometimes unreliable and, during the initial battles, medical practitioners supporting combat troops had to practice ingenuity and improvisation. During the battles, 225 British Soldiers were killed and 777 wounded. Of the wounded who presented at the British Advanced Surgical Centers, only 7 subsequently died (1%). 658 battle casualties were dealt with at the various land-based surgical facilities. About 270 general anesthetics were given.

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Ketamine Induction in Poor-Risk Patients

Cited by 7 publications

References 0 publications

Overdosage of Ketamine Anaesthetic Agent in Cats with Special Reference to Clinical Assessment

Overdosage of Ketamine Anaesthetic Agent in Cats with Special Reference to Clinical Assessment

The Future of Intensive Care Unit Sedation: A Report of Continuous Infusion Ketamine as an Alternative Sedative Agent

The Falkland Islands Campaign Resuscitation and Anesthesia in a Battle Situation

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