Ketamine Compared With Fentanyl for Surgical Abortion

Chin, Jennifer; McGrath, Madeline; Lokken, Erica; Upegui, Carlos Delgado; Prager, Sarah; Micks, Elizabeth

doi:10.1097/aog.0000000000004903

“…Our endpoints for repeated administration of either medication in each arm were defined in our article and are per clinic standard: ".if the participant was moving so much that it was unsafe to continue the procedure, if the participant was reporting pain, or if the participant was otherwise not tolerating the procedure." 1 In this way, we ensured that all patients received Guidelines for Letters. Letters posing a question or challenge to an article appearing in Obstetrics & Gynecology should be submitted within 8 weeks of the article's publication online.…”

Section: In Replymentioning

confidence: 99%

“…We read the article by Chin et al 1 in the September 2022 issue of the journal with great enthusiasm. The authors conclude that, compared with intravenous fentanyl, intravenous ketamine is noninferior for patient satisfaction with anesthesia when used for procedural sedation for surgical abortion, which is not surprising.…”

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confidence: 99%

Ketamine Compared With Fentanyl for Surgical Abortion: A Randomized Controlled Trial

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Jha

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2023

Obstetrics &Amp; Gynecology

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“…Weyand and Flores on our article in the September 2022 issue. 1 We agree that procedural opioids are unlikely to substantially contribute to the opioid epidemic; however, we feel that decreased reliance on opioids is an important goal on a societal level. Fentanyl may indeed be a better option in selected patients.…”

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confidence: 91%

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Chin

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,

Micks

²

2023

Obstetrics &Amp; Gynecology

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adequate anesthesia. We chose this patient-centered outcome, because we know patients who undergo abortion are generally satisfied with their care. 2 More recent studies have recommended patient-centered outcomes as a more accurate measure of patient experience during an abortion procedure; thus, we feel this was an appropriate measurement. 3 The duration of the intervention was the duration of the abortion procedure, which typically lasts 10 minutes or less. We decided to assess satisfaction both immediately after the procedure as well as on postoperative day 1 to see whether there were any differences between the groups at both time points; we found no significant differences. We allowed anesthetists to provide rescue medications of their choosing as per clinic standard. As much as possible, we kept patient treatment during our study similar to standard clinic practice because we wanted to look at real-world use of both of these medications.

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“…We read the article by Chin et al 1 in the September 2022 issue with great interest. As anesthesiologists and advocates for women's health, we laud the authors for examining areas to make abortion care as safe and accessible as possible.…”

mentioning

confidence: 99%

Ketamine Compared with Fentanyl for Surgical Abortion: A Randomized Controlled Trial

Weyand

¹

,

Flores

²

2023

Obstetrics &Amp; Gynecology

0

View full text Add to dashboard Cite

adequate anesthesia. We chose this patient-centered outcome, because we know patients who undergo abortion are generally satisfied with their care. 2 More recent studies have recommended patient-centered outcomes as a more accurate measure of patient experience during an abortion procedure; thus, we feel this was an appropriate measurement. 3 The duration of the intervention was the duration of the abortion procedure, which typically lasts 10 minutes or less. We decided to assess satisfaction both immediately after the procedure as well as on postoperative day 1 to see whether there were any differences between the groups at both time points; we found no significant differences. We allowed anesthetists to provide rescue medications of their choosing as per clinic standard. As much as possible, we kept patient treatment during our study similar to standard clinic practice because we wanted to look at real-world use of both of these medications.

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Ketamine Compared With Fentanyl for Surgical Abortion

Abstract: Intravenous ketamine is noninferior to intravenous fentanyl for patient satisfaction with anesthesia during first-trimester surgical abortion.

Cited by 8 publications

References 23 publications

Ketamine Compared With Fentanyl for Surgical Abortion: A Randomized Controlled Trial

Ketamine Compared With Fentanyl for Surgical Abortion: A Randomized Controlled Trial

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Ketamine Compared with Fentanyl for Surgical Abortion: A Randomized Controlled Trial

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