1986
DOI: 10.1016/s0190-9622(86)70111-4
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Keratotic lupus erythematosus: Treatment with isotretinoin

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Cited by 47 publications
(20 citation statements)
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“…These KA-like proliferations respond to retinoids and steroids, offering supportive evidence that they are HLE-related rather than neoplastic proliferations. 3,4 In some patients, hyperkeratotic lesions may evolve into cribriform scars. Cutaneous manifestations may be chronic and progressive, but systemic LE is not present in most cases.…”
Section: Pathologic Findingsmentioning
confidence: 99%
“…These KA-like proliferations respond to retinoids and steroids, offering supportive evidence that they are HLE-related rather than neoplastic proliferations. 3,4 In some patients, hyperkeratotic lesions may evolve into cribriform scars. Cutaneous manifestations may be chronic and progressive, but systemic LE is not present in most cases.…”
Section: Pathologic Findingsmentioning
confidence: 99%
“…[69] Acitretin, isotretinoin and combination therapy of isotretinoin with hydroxychloroquine have been used to treat resistant hypertrophic lupus erythematosus, but the response is usually short-lived and maintenance therapy is required. In our case, combination of isotretinoin with hydroxychloroquine proved highly effective and the hyperkeratotic plaques disappeared promptly within the first three months of treatment but the patient relapsed after stopping the therapy; so he was started on isotretinoin again.…”
Section: Discussionmentioning
confidence: 99%
“…Systemic retinoids can be used alone or in combination with antimalarials. Acitretin (11, 12), isotretinoin (6) or a combination therapy of isotretinoin with hydroxychloroquin (4) have been reported to be successful in treating resistant hypertrophic LE.…”
Section: Discussionmentioning
confidence: 99%