Keratoprosthesis Surgery as an Alternative to Keratoplasty

Jašinskas, Vytautas; Rudalevičius, Paulius; Miliauskas, Arūnas; Milčius, D.; Jurkūnas, Ūla V.

doi:10.3390/medicina49060046

Cited by 4 publications

(9 citation statements)

References 12 publications

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“…Implantation of an artificial cornea (i.e. keratoprosthesis) is a good option for the eyes which has low success rates of corneal transplant surgery such as comorbid limbal stem cell deficiency due to chemical or thermal burns, viral keratitis, ocular cicatricial pemphigoid, trachoma and repeated transplantation [12–14]. …”

Section: Discussionmentioning

confidence: 99%

Publication trends in corneal transplantation: a bibliometric analysis

Pekel

2016

BMC Ophthalmol

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BackgroundOur aim was to demonstrate the publication trends of corneal transplantation in the last decade.MethodsAll of the keratoplasty research articles, letters, case reports, reviews and meeting abstracts published between January 2006 and December 2015 indexed on the Thomson Reuters Web of Knowledge were evaluated. A bibliometric filter was used to capture keratoplasty related publications by using the key words ‘keratoplasty’, ‘corneal transplantation’ or ‘keratoprosthesis’ in the ‘title’ selection mode.ResultsA total of 2726 publications were evaluated in the present study. Documents related to penetrating keratoplasty only have been decreased, whereas the documents related to endothelial keratoplasty were increased in the last decade. The total keratoplasty publication counts had been increased from the year 2006 to 2015. The average citation count per keratoplasty documents was 9.34.ConclusionsThere is a growing interest to the lamellar keratoplasty techniques especially the endothelial keratoplasty in the last decade.

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Section: Discussionmentioning

confidence: 99%

Publication trends in corneal transplantation: a bibliometric analysis

Pekel

2016

BMC Ophthalmol

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“…While bullous keratopathy and aniridia were reported commonly in the studies from the US and Canada, post-trachomatous scarring 15 was the most common indication from Saudi Arabia (Fig. 1) and chemical injury was the common indication internationally 7,12,13,16,17,20,23,34,38 . Thus the indications for B-Kpro from different geographical regions vary due to differences in the causes of corneal blindness.…”

Section: Clinical Outcomesmentioning

confidence: 98%

“…Literature review also seems to suggest that indication of primary B-KPro implantation (KPro implantation performed without first attempting keratoplasty) included eyes with severe ocular surface damage due to chemical or thermal injury (percentages varying from 7% to 30.4% in different studies) (Table 1) 9,11,15–17,31–35 or autoimmune diseases such as SJS (2.5–100%) 8–11,16,34,35 or congenital anomalies such as aniridia (1–100%) 12,17,23,34–37 . While bullous keratopathy and aniridia were reported commonly in the studies from the US and Canada, post-trachomatous scarring 15 was the most common indication from Saudi Arabia (Fig.…”

Section: Clinical Outcomesmentioning

confidence: 99%

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Boston keratoprosthesis – Clinical outcomes with wider geographic use and expanding indications – A systematic review

Arfaj

2015

Saudi Journal of Ophthalmology

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Over 2 decades of research, several design modifications, and improvements in post-operative management have made Boston keratoprosthesis (B-KPro) a viable option for patients with corneal blindness for whom traditional keratoplasty procedure has a very low probability of success. In this systematic review, we examined the indications, visual outcomes, complications and retention rate of the literature published in the past 10 years (2005-2014). While most of the studies report smaller datasets (typically <50 eyes), some of the recent multicenter studies have reported large datasets (up to 300 eyes). Most of the literature is published from the US; however, last few years have witnessed some papers reporting the successful use of B-Kpro from developing countries or arid climatic conditions (such as the Kingdom of Saudi Arabia). Due to differences in the causes of corneal blindness in different geographic regions, newer indications for B-Kpro are emerging (e.g. trachoma). Additionally, improving clinical outcomes and increasing surgeon confidence have also expanded indications to include cases of unilateral visual impairment and paediatric age. We observed that there is growing body of evidence of successful clinical use of B-KPro; however, financial challenges, lack of trained surgeons, shortage of donor corneas must be overcome to improve accessibility of B-KPro.

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“…2 KPro is now used for treating patients with multiple prior graft failures, chemical or thermal burns, aniridia, trauma, herpetic keratitis, Stevens-Johnson syndrome, and others. 3 Scholarly clinical research related to KPro outcomes is abundant in the literature. 3 Scholarly clinical research related to KPro outcomes is abundant in the literature.…”

mentioning

confidence: 99%