Keratophakia and Keratomileusis — Clinical Results

Swinger, Casimir A.; Barraquer, J

doi:10.1016/s0161-6420(81)34958-6

Cited by 91 publications

(7 citation statements)

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“…Stromal keratophakia or tissue additive keratoplasty may offer the solution to the shortcomings of the current treatment modalities for keratoconus [21,22]. The initial iteration of the technique, as introduced by Prof. José Ignacio Barraquer, had significant technological limitations and hence produced inconsistent results and was associated with significant postoperative complications [21,23].…”

Section: Introductionmentioning

confidence: 99%

Femtosecond laser-assisted stromal keratophakia for keratoconus: A systemic review and meta-analysis

et al. 2021

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Purpose Femtosecond lasers have revived the possibility of stromal keratophakia or tissue additive keratoplasty, a technique originally introduced by Prof. Jose Ignacio Barraquer in the 1960s. The surgical technique offers a unique solution to treat keratoconus. In the current study, we reviewed and performed a meta-analysis of the clinical outcomes of the femtosecond laser-assisted stromal keratophakia in the treatment of keratoconus. Methods This is a systematic review and metaanalysis of the estimated outcome difference between pre-and post-lenticule implantations. Results A total of related 10 studies were found in the literature. No studies reported adverse events, such as persistent haze or graft rejection, at last patients' visits. We further narrowed down the article selection in accordance to our inclusion criteria to report the composite outcomes (9 studies) and meta-analysis (4 studies). In the composite analysis, we demonstrated that lenticule implantation in keratoconus and post-LASIK ectasia patients appeared to expand the stromal volume of the thin corneas, flattened the cones, and significantly improved uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA) and spherical equivalent (SE). The meta-analysis showed that the random estimated UCVA, BCVA, SE and mean keratometry (K m ) differences following the lenticule implantation was -0.214 (95% CI: -0.367 to 0.060; p = 0.006), -0.169 (-0.246 to 0.091; p \ 0.001), -2.294 D (-3.750 to -0.839 D;

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Section: Introductionmentioning

confidence: 99%

Femtosecond laser-assisted stromal keratophakia for keratoconus: A systemic review and meta-analysis

et al. 2021

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“…Pioneered for years by Barraquer of Bogota, Colombia, keratomileusis and keratophakia have recently been introduced into the United States. 23 Simpler variations of these techniques have been developed, such as the technique of epikeratophakia, in which an onlay donor graft, which has been prefrozen and lathed, is sutured onto the surface of the cornea after the corneal epithelium has been removed. 13 In other approaches, hydrophilic materials or precut donor .corneas have been used to replace the donor corneal lenticules.…”

Section: Correction Of Aphakiamentioning

confidence: 99%

Cataracts and Cataract Operations (First of Two Parts)

Liesegang¹

1984

Mayo Clinic Proceedings

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“…He invented the microkeratome and developed the surgical procedures of keratomileusis and keratophakia 1,2. The former eventually evolved into laser-assisted in situ keratomileusis (LASIK) by Pallikaris et al3 Since then it has been widely used mainly to correct myopic refractive errors, flattening and thinning the central cornea.…”

Section: Introductionmentioning

confidence: 99%

Axial eye length measurements pre- and post- laser-assisted in situ keratomileusis using the IOL Master: a pilot study

Chalkiadakis¹,

Amariotakis²,

Parikakis³

et al. 2010

OPTH

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PurposeA preliminary study in order to test the accuracy of the IOL Master in detecting axial eye length changes after laser-assisted in situ keratomileusis and to correlate the findings with the theoretical ablation depth.MethodsPre-and postoperative axial eye length measurements were performed in 10 consecutive eyes that underwent laser-assisted in situ keratomileusis with the Alcon Ladar Vision excimer laser to treat myopic refractive errors ranging from −2.50 to −8.00 diopters of spherical equivalent (mean: −5.23 ± 1.30 D).ResultsThe preoperative axial eye length measurements ranged from 24.53 mm to 27.78 mm (mean: 25.80 ± 1.01 mm) and from 24.57 mm to 27.57 mm (mean: 25.68 ± 0.93 mm) 1 month after the operation. Preoperative and 1-month postoperative data showed a statistically significant difference (P < 0.05).ConclusionsThe IOL Master showed a decrease in the axial eye length measurements that was bigger than the theoretical ablation depth and did not correlate well with it. Such data need to be confirmed by a larger cohort of patients.

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Keratophakia and Keratomileusis — Clinical Results

Cited by 91 publications

References 1 publication

Femtosecond laser-assisted stromal keratophakia for keratoconus: A systemic review and meta-analysis

Femtosecond laser-assisted stromal keratophakia for keratoconus: A systemic review and meta-analysis

Cataracts and Cataract Operations (First of Two Parts)

Axial eye length measurements pre- and post- laser-assisted in situ keratomileusis using the IOL Master: a pilot study

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