Keratocystoma of minor salivary gland of the palate

Keratocystoma of the parotid gland is rare and requires an integrated multidisciplinary approach: Report of a case and a literature review

“…Immunohistochemical investigation showed positivity for CK AE1/AE3, CK 5, p63, and p40 and negativity for CK 8/18. Ki‐67 was expressed by a few cells in the basal layer, as in other reported cases . Infection‐related markers EBER and HPV were negative.…”

“…Solid epithelial cell nests without cytological atypia can also be evident. Our case presented all of the morphologic and immunohistochemical features of previously reported cases (summarized in Table ). The presence of mature squamous cells in parotid FNA can be due to benign entities, chronic obstruction, and dilation of ductal trees with squamous metaplasia, ameloblastoma with squamous metaplasia, primitive carcinoma, or metastasis of well‐differentiated squamous carcinoma.…”

“…Ki-67 was expressed by a few cells in the basal layer, as in other reported cases. [2][3][4][5][6][7] Infection-related markers EBER and HPV were negative. A list of all antibodies used is summarized in Table 1.…”

Cystic lesion in parotid region: an unexpected diagnosis

“…So, our case report is disagreed with current literature: actually, our patient was in her mid-70s. Moreover, only one case8 described a keratocystoma in the minor salivary gland of soft palate.…”

“…Keratocystoma is a rare benign tumour of the salivary glands with very few cases in the world reported in scientific literature 1–8. Initially described by Seifert et al 3 9 as an unusual mass called choristoma, it was later studied by Nagao et al 1 calling it keratocystoma.…”