Keratoconus and Visual Performance with Different Contact Lenses

Marta, Ana; Marques, João Heitor; Almeida, Daniel; José, Diana; Barbosa, Irene

doi:10.2147/opth.s345154

Cited by 4 publications

(2 citation statements)

References 28 publications

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“…Spectacles are a suitable treatment option for early-stage KCN in patients with a visual acuity of 20/40 or better [ 37 ] . However, they cannot rectify the irregular astigmatism associated with KCN [ 38 ] .…”

Section: Resultsmentioning

confidence: 99%

Keratoconus: imaging modalities and management

Alqudah

2024

Med Hypothesis Discov Innov Ophthalmol

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Background: Keratoconus (KCN) is characterized by gradual thinning and steepening of the cornea, which can lead to significant vision problems owing to high astigmatism, corneal scarring, or even corneal perforation. The detection of KCN in its early stages is crucial for effective treatment. In this review, we describe current advances in the diagnosis and treatment of KCN. Methods: This narrative review focuses on recent advancements in the diagnosis and treatment of KCN, especially evolving approaches and strategies. To ensure the inclusion of the most recent literature, relevant publications discussing advanced imaging techniques and treatment options for KCN were extensively gathered from the PubMed/MEDLINE and Google Scholar databases. The following index terms and keywords were used for the online search: keratoconus, diagnosis of keratoconus, advances in the diagnosis of keratoconus, topography or tomography, anterior segment optical coherence tomography, treatment of keratoconus, advances in the treatment of keratoconus, collagen crosslinking, intrastromal ring, keratoplasty, and new techniques in keratoconus. Results: Various screening methods such as corneal topography, tomography, anterior segment optical coherence tomography, and assessment of corneal biomechanics have been developed to identify KCN in its early stages. After diagnosis, KCN management focuses on preventing disease progression. Corneal collagen crosslinking is a minimally invasive treatment that can slow or stop the progression of the condition. Recent research has also explored the use of copper sulfate eye drops (IVMED-80) as a noninvasive treatment to prevent the progression of KCN. Current treatment options for visual improvement include scleral lenses, intracorneal ring segments, corneal allogeneic intrastromal ring segments, and deep anterior lamellar keratoplasty. Recently, novel alternative procedures, such as isolated Bowman layer transplantation, either as a corneal stromal inlay or onlay, have demonstrated encouraging outcomes. Artificial intelligence has gained acceptance for providing best practices for the diagnosis and management of KCN, and the science of its application is contentiously debated; however, it may not have been sufficiently developed. Conclusions: Early detection and advancements in screening methods using current imaging modalities have improved diagnosis of KCN. Improvement in the accuracy of current screening or diagnostic tests and comparison of their validities are achievable by well-designed, large-scale, prospective studies. The safety and effectiveness of emerging treatments for KCN are currently being investigated. There is an ongoing need for studies to track progress and evaluate clinicians’ knowledge and practices in treating patients with KCN. Artificial intelligence capabilities in management approach considering the currently available imaging modalities and treatment options would best benefit the patient.

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Section: Resultsmentioning

confidence: 99%

Keratoconus: imaging modalities and management

Alqudah

2024

Med Hypothesis Discov Innov Ophthalmol

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“…Although the development of other treatment methods continues rapidly, the application of RGPCL is still the primary treatment option for vision quality [6]. The usage of rigid contact lenses in individuals with keratoconus has become compatible in recent years, with the production of highly gas permeable and ultraviolet light-blocking RGPCL materials that do not disrupt the corneal physiology [7]. However, little is known regarding the effect of rigid contact lens wear on keratokonus progression over a long time.…”

Section: Introductionmentioning

confidence: 99%

Effects of rigid high gas-permeable contact lens wear on progression in patient with keratoconus

Yılmaz¹,

Durhan²,

Altin³

et al. 2022

Med-Science

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Wearing Rigid High Gas-Permeable Contact Lens (RGPCL) is a primary method of vision rehabilitation in keratoconus eyes. The aim of the study is to investigate the effects of using RGPCL on the topographical variations at the keratoconus progress. All patients had undergone ophthalmic examination including corneal topography, and their medical history and keratoconus characteristics were documented. Fifty-one eyes of those who wore RGPCL without any problems and 42 eyes of those who did not wear any lenses were evaluated retrospectively. It was accepted that the follow-up period was terminated when patients received any treatment or change lenses. The mean follow-ups were 36.5±12.7 and 38.4±14.6 months in the control and lens-wearing samples, respectively. The changes in topographic indices were compared from the baseline to the final visit. The difference between spectacle-best corrected visual acuity was not significant in both groups from baseline to final visit (p>0.05). In the RGPCL wearing group, apical keratometric power ( Kmax ) increased from mean 51.86±3.70 diopter (D) to 52.54±3.85 D at the sagittal map in the following period, but this difference was not significant (p>0.05). Similarly, in the control group, Kmax increased from mean 52.14±2.51 D to 52.94±3.02 D, and this difference was not significant (p>0.05). Lens-wearing and control group mean keratometry values increased from 47.36±1.7 D and 47.17±1.65 D to 47.94±2.05 D and 47.74±1.76 D, respectively (p>0.05). Pachymetry at the thinnest corneal point decreased significantly in both groups from baseline to final visit (p=0.008, p=0.01). In conclusion, the comfortable usage of RGPCL has no effect on the progression of keratoconus.

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Computational analysis of retinal image quality with different contact lens designs in keratoconus

Devi¹,

Kumar²

2023

Contact Lens and Anterior Eye

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Keratoconus and Visual Performance with Different Contact Lenses

Cited by 4 publications

References 28 publications

Keratoconus: imaging modalities and management

Keratoconus: imaging modalities and management

Effects of rigid high gas-permeable contact lens wear on progression in patient with keratoconus

Computational analysis of retinal image quality with different contact lens designs in keratoconus

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