Keratitis from abuse of corneal anaesthetics.

Henkes, H.E.; Waubke, Th. N.

doi:10.1136/bjo.62.1.62

Cited by 42 publications

(19 citation statements)

References 1 publication

(1 reference statement)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Topical anesthetic abuse has been reported to cause mild to severe corneal disorders, [3][4][5][6][7][8] including superficial punctate keratopathy, persistent epithelial defect, Wessely immune ring-like or disciform stromal infiltration, stromal edema, Descemet membrane folding, and endothelial cell loss. More devastating side effects, such as neurotrophic ulcer, secondary infectious keratitis, corneal perforation, and subsequent permanent visual loss may also develop.…”

Section: Discussionmentioning

confidence: 99%

Toxic Keratopathy Associated With Abuse of Low-Dose Anesthetic

Chen

Hsu

2004

Cornea

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Toxic Keratopathy Associated With Abuse of Low-Dose Anesthetic

Chen

Hsu

2004

Cornea

View full text Add to dashboard Cite

show abstract

“…DR consists of a microangiopathy that induces pathological changes of the vascular structures and the blood rheological properties as a consequence of chronic hyperglycemia. 66–68 Recently, DR has been postulated to be a multifactorial disease involving the retinal neuronal cells. 69–73 The neurodegenerative change consists of apoptosis of several populations, including photoreceptors, bipolar and ganglion cells.…”

Section: Clinical Applications Of Ao Retinal Imagingmentioning

confidence: 99%

Adaptive Optics Retinal Imaging – Clinical Opportunities and Challenges

Carroll

Kay²,

Scoles

et al. 2013

Current Eye Research

View full text Add to dashboard Cite

The array of therapeutic options available to clinicians for treating retinal disease is expanding. With these advances comes the need for better understanding of the etiology of these diseases on a cellular level as well as improved non-invasive tools for identifying the best candidates for given therapies and monitoring the efficacy of those therapies. While spectral domain optical coherence tomography (SD-OCT) offers a widely available tool for clinicians to assay the living retina, it suffers from poor lateral resolution due to the eye’s monochromatic aberrations. Adaptive optics (AO) is a technique to compensate for the eye’s aberrations and provide nearly diffraction-limited resolution. The result is the ability to visualize the living retina with cellular resolution. While AO is unquestionably a powerful research tool, many clinicians remain undecided on the clinical potential of AO imaging – putting many at a crossroads with respect to adoption of this technology. This review will briefly summarize the current state of AO retinal imaging, discuss current as well as future clinical applications of AO retinal imaging, and finally provide some discussion of research needs to facilitate more widespread clinical use.

show abstract

“…Three similar cases were reported in Holland by Henkes and Waubke (1978), these patients having developed a physical dependence on the drops because of the intense pain in the insensitive cornea. The local anaesthetics in these cases were supplied by an ophthalmologist.…”

Section: Adverse Reactions To Local Anaestheticsmentioning

confidence: 59%