Kell immunization: A case report

Tasić, Marija; Milošević, Jelena; Stefanović, Milan; Radovic-Janosevic, Dragana; Krstić, Miljan; Antić, Vladimir

doi:10.2298/mpns0908369t

Cited by 1 publication

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References 8 publications

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“…60 % of the sample. Our results show an increase in the frequency of Kell antibodies (5.4 %) during pregnancy, which has been confirmed by studies carried out in neighboring countries [13,14]. Non-Rh D antibodies are a potential constant threat to pregnant women and the incidence of HDN, since effective prevention measures against the non-Rh D sensitization of pregnant women do not yet exist [9].…”

Section: Discussionsupporting

confidence: 86%

The Incidence and Effects of Alloimmunization in Pregnancy During the Period 2000 – 2013

Raguž

Glamuzina

Brzica

et al. 2017

Geburtshilfe Frauenheilkd

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ABSTR AC T IntroductionThe objective of the analysis was to examine the epidemiological aspects of maternal alloimmunization and to determine the most common antibody specificities resulting in hemolytic disease of the newborn (HDN). Materials and MethodsThe retrospective epidemiological study encompasses all pregnant women who underwent immunohematological screening and the newborn treated for HDN in the period from 2000 to 2013 in the Herzegovina region. ResultsThe indirect Coombs test (ICT) detected antibodies against antigens in 384 (2.4 %) pregnant women of the 18 800 who were tested at the Department of Transfusion Medicine. The direct Coombs test (DCT) detected antibodies against antigens in 160 (0.8 %) newborn treated for HDN. The results of our 13-year study, in which 60 % of the pregnant women had non-RhD antibodies, confirms this finding.Conclusion However, we have reached the 21st century and the burden of alloimmunisation in pregnancy is still on our backs. The problem of immunization and HDN is still present in our region, which is a neonatal and public health problem.

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Section: Discussionsupporting

confidence: 86%