Keep the corners; adriamycin nephropathy

Abstract

Adriamycin is an anticancer agent with broad-spectrum efficacy against tumors. However, chemotherapy-induced renal toxicity constraints clinical efficacy of cancer treatment. The nephropathy of adriamycin is detected by podocyte damage and foot process effacement, which followed by glomerulosclerosis and inflammation in the tubulointerstitial area and fibrosis.