KEANEKARAGAMAN RAMBAI (Baccaurea motleyana (Müll.Arg.) Müll.Arg.) DI PULAU BENGKALIS BERDASARKAN KARAKTER MORFOLOGI

Ramayani, Putri; Fitmawati,

doi:10.14203/bkr.v23i1.5

Cited by 7 publications

(8 citation statements)

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“…Salah satu tumbuhan yang memiliki khasiat sebagai kandidat obat diabetes adalah kulit buah rambai . Indonesia memiliki keanekaragaman hayati tumbuhan khususnya tumbuhan rambai (Ramayani & Fitmawati, 2020).…”

Section: Pendahuluanunclassified

Uji Toksisitas Makroskopis Pada Organ Ginjal, Hati, Jantung dan Limpa Mencit Hiperglikemia yang Diberi Ekstrak Etanol Kulit Buah Rambai (Baccaurea motleyana)

Ceriana,

Putri Rejeki

2023

jharma

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Diabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia. Plants that can reduce blood sugar levels in alloxan-induced mice are Rambai peel (Baccaurea motleyana). The safety of the use of plants as herbal medicine must be known so as not to cause unwanted harmful effects. In this study, the relative weight of organs and changes in organ appearance were observed macroscopically. The design in this study was a completely randomized design with 24 male mice divided into 6 treatments and 4 replications. The treatment consisted of a negative control (Aquadest), a positive control (glibenclamide), peel Rambai ethanol extract with graded doses of 200 mg/kg, 400 mg/kg, 800 mg/kg and 1600 mg/kg. , given orally. The results showed that the ethanol extract of Rambai peel had no significant effect on the relative weight of the heart, kidneys and spleen, but had a significant effect on the relative weight of the liver. The results of this study also showed that no color changes were seen in any of the mice organs. So, this study showed no visible macroscopic changes in the organs, so that administration of Rammbai ethanol extract gradually causes fewer toxic effects and is still considered safe in experimental animals.

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Section: Pendahuluanunclassified

Uji Toksisitas Makroskopis Pada Organ Ginjal, Hati, Jantung dan Limpa Mencit Hiperglikemia yang Diberi Ekstrak Etanol Kulit Buah Rambai (Baccaurea motleyana)

Ceriana,

Putri Rejeki

2023

jharma

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“…This plant serves as a medicinal plant, with applications in treating eye and skin inflammation. Additionally, rambai’s ecological significance extends to being a food source for various animals, including birds, rodents, deer, monkeys, and orangutans ( Ramayani, 2020 ). Evidence showed that B. motleyana exhibits diverse medicinal uses across various cultures.…”

Section: Introductionmentioning

confidence: 99%

Phyto-pharmacological evaluation and characterization of the methanolic extract of the Baccaurea motleyana Müll. Arg. seed: promising insights into its therapeutic uses

Shompa,

Hasnat,

Riti

et al. 2024

Front. Pharmacol.

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Introduction: Plants and their extracts have been integral to the development of medicinal treatments throughout history, offering a vast array of compounds for innovative therapies. Baccaurea motleyana Müll. Arg., commonly known as Rambai, is an evergreen tree with economic importance in the Old-World Tropics.Method: The study investigates its phytochemical composition through Gas Chromatography-Mass Spectrometry (GC-MS) and evaluates its pharmacological properties, including antidiabetic, antidiarrheal, antimicrobial, and antidepressant effects.Result and Discussion: The GC-MS analysis revealed 15 bioactive compounds in the methanol extract, with Phenol, 3,5-bis(1,1-dimethylethyl)-, Methyl stearate, and Hexadecanoic acid, methyl ester being the predominant ones. The cytotoxicity assay demonstrated significant activity in the ethyl acetate fraction. Antimicrobial assays indicated mild to moderate antibacterial activity. In vivo studies on mice revealed significant hypoglycemic, antidiarrheal, and antidepressant properties. Molecular docking studies against EGFR, DHFR, GLUT-3, KOR, and MOA identified promising compounds with potential therapeutic effects. The identified compounds exhibited favorable ADME/T properties, emphasizing their potential for drug development. The study underscores the promising therapeutic potential of Baccaurea motleyana, showcasing its diverse bioactive compounds with significant medicinal properties.Conclusion: These findings lay the groundwork for future research, emphasizing the exploration of B. motleyana as a source of natural remedies for addressing prevalent health conditions.

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“…Durian is a tropical fruit that has unique flavor and aroma. Durian is also called the king of fruit which is very popular among other fruits because of its distinctive taste (Lestari et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Genetic Diversity of Durian (Durio zibethinus Murr.) from North and South Nias using Simple Sequence Repeat (SSR)

Ndruru,

Saleha Hannum,

Suci Rahayu

2023

Int J Ecophysiol

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Durian is a tropical fruit that has economic value for Nias Island especially in North and South Nias. Anthropogenic activity already occured in Nias and caused disturbance resulting in destruction and extinction of various durian. The aim of the research was to analyzed the genetic diversity of Durian from North and South Nias using SSR primers namely: Dz844, DzGCCG01, DzGCAG01, and DzMTb021. Total DNA was successfully isolated from 20 accessions. The DNA was successfully amplified resulting in DNA alleles sizing from 170-1100 bp. All primers showed 33 alleles with 28 polymorphic bands. The DNA profile were further analyzed with Ntsys which showed that 20 accession has coefficient of similarity 0.66-0.94 and clustered into nine groups at the similarity coefficient of 0.80. The research showed that the ninth accession of durian from North and South Nias has a high genetic diversity.

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KEANEKARAGAMAN RAMBAI (Baccaurea motleyana (Müll.Arg.) Müll.Arg.) DI PULAU BENGKALIS BERDASARKAN KARAKTER MORFOLOGI

Cited by 7 publications

References 0 publications

Uji Toksisitas Makroskopis Pada Organ Ginjal, Hati, Jantung dan Limpa Mencit Hiperglikemia yang Diberi Ekstrak Etanol Kulit Buah Rambai (Baccaurea motleyana)

Uji Toksisitas Makroskopis Pada Organ Ginjal, Hati, Jantung dan Limpa Mencit Hiperglikemia yang Diberi Ekstrak Etanol Kulit Buah Rambai (Baccaurea motleyana)

Phyto-pharmacological evaluation and characterization of the methanolic extract of the Baccaurea motleyana Müll. Arg. seed: promising insights into its therapeutic uses

Genetic Diversity of Durian (Durio zibethinus Murr.) from North and South Nias using Simple Sequence Repeat (SSR)

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