Kawasaki disease in infants less than one year of age

Rosenfeld, Elaine A.; Corydon, Kathleen; Shulman, Stanford T.

doi:10.1016/s0022-3476(95)70344-6

Cited by 193 publications

(133 citation statements)

References 11 publications

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“…Low serum albumin level, young age at diagnosis, and long duration of fever have been identified previously as high-risk factors of CAL development. [32][33][34] Data from this current study show that male gender, young age at diagnosis, and long duration of fever are independent risk factors of CALs.…”

Section: Discussionmentioning

confidence: 53%

“…Many previous studies have looked at putative predictors of CAL development in KD including demographic, clinical, and laboratory variables. [32][33][34][35] Harada 36 suggested a set of high-risk criteria to allocate limited IVIg therapy rationally. None of these studies have addressed the effect of concurrent infections on coronary artery outcome.…”

Section: Discussionmentioning

confidence: 99%

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Infections and Kawasaki Disease: Implications for Coronary Artery Outcome

et al. 2005

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ABSTRACT. Objective. We sought to determine the effect of coincident infection, at time of diagnosis of Kawasaki disease (KD), on treatment response and coronary artery outcome.Methods. A single-center, retrospective study of 129 consecutive patients diagnosed with typical KD between January 1997 and December 1998 was performed. Standardized clinical assessments, laboratory, microbiology, and imaging test results plus treatment regimens were reviewed. Coronary arteries were visualized by using echocardiography, and coronary artery lesions (CALs) were reported as body surface area-adjusted z scores. Infectionpositive and -negative groups were identified, and clinical, laboratory, and treatment data were analyzed. The effect of infections and other outcome variables on CAL development was determined by multivariate regression analysis.Results.

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Infections and Kawasaki Disease: Implications for Coronary Artery Outcome

et al. 2005

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“…Young infants with KD are at increased risk for formation of coronary artery aneurysms due to delayed diagnosis and decreased responsiveness to IVIG treatment (8). In addition to his age our patient had other bad prognostic signs including male sex, prolonged fever in spite of IVIG treatment, anemia and hypoalbuminemia.…”

Section: Resultsmentioning

confidence: 78%

Kawasaki disease presenting as meningitis in a two months old infant

Türel¹,

Güzeltaş²,

Aydoğmuş³

et al. 2011

Anadolu Kardiyol Derg

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“…El 13% son menores de 1 año y el 3% son menores de 6 meses de edad; el 80% de los casos ocurren en menores de 5 años de edad, y el 90% en menores de 8 años de edad, y hay casos descritos hasta la edad de 15 años (3,4). La incidencia en el sexo masculino es de 1.5 a 1 con respecto al sexo femenino (2).…”

Section: Discusionunclassified

Enfermedad de Kawasaki: un caso con pseudo-obstrucción intestinal y aneurisma gigante

Tori¹,

Galgani²

2015

Rev Med Hered

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SUMMARYWe present a rare association of Kawasaki disease in a two year old boy presenting with fever, a morbiliform rash and clinical signs of intestinal pseudo-obstruction. Our patient subsequently developed a giant aneurysm of the right coronary artery complicated with thrombosis. He presented fever again 48 hours after the first dose of Immunoglobulin and needed a second one with good results. These patients with giant coronary aneurysms have a greater risk of developing stenosis and myocardial infarction, and require anticoagulant therapy, frequent stress scans and coronary angiographies. Those who developed less severe disease need only antiplatelet therapy and less frequent cardiovascular tests. Patients with a normal echocardiogram after the acute phase of the disease are not treated. The long-term prognosis of this disease is uncertain, especially regarding the possible association with coronary disease in adult life. (Rev Med Hed 2002; 13: 114-122).KEY WORDS: Kawasaki, mucocutaneous lymph node syndrome, vasculitis, pseudoobstruction, coronaryaneurysms. INTRODUCCIÓNPresentamos a un paciente varón de dos años de edad con Enfermedad de Kawasaki y secuelas cardiovasculares. Se presentó como un cuadro febril, signos abdominales sugestivos de un cuadro suboclusivo intestinal y un rash morbiliforme en el cuerpo. Durante su evolución inmediata los tramos iniciales de las dos arterias coronarias principales fueron aumentando de tamaño hasta convertirse la arteria coronaria derecha en un aneurisma gigante de 9.7 mm de diámetro, que desarrolló un trombo aunque sin mayores complicaciones.Debido a su compromiso cardiovascular, nuestro paciente presenta un gran riesgo de desarrollar estenosis coronaria, razón por la cual tiene que ser evaluado periódicamente.A pesar que la Enfermedad de Kawasaki es una enfermedad poco común, sin embargo, su forma de presentación y los signos y síntomas que presenta, la hacen confundirse con otras enfermedades más usuales, lo que hace que se demore o no se haga el diagnóstico a tiempo y poder así evitar secuelas tan importantes como el aneurisma gigante que presentó este paciente a pesar que el diagnóstico fue hecho con prontitud. Caso Clínico:Paciente varón de 2 años de edad, con historia de fiebre alta, dolor abdominal y constipación. Se inicia con dolor abdominal difuso tipo cólico, dos días antes de su ingreso y que fué aumentando en intensidad en las 24 horas previas a su ingreso. No eliminaba flatos y no había

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Kawasaki disease in infants less than one year of age

Cited by 193 publications

References 11 publications

Infections and Kawasaki Disease: Implications for Coronary Artery Outcome

Infections and Kawasaki Disease: Implications for Coronary Artery Outcome

Kawasaki disease presenting as meningitis in a two months old infant

Enfermedad de Kawasaki: un caso con pseudo-obstrucción intestinal y aneurisma gigante

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