Kaposi sarcoma involving bone in an HIV negative patient

Martínez-Sapiña, M.J.; Mosquera, Jorge; Castro, J.M.; Comesaña, M.L.; Rodrı́guez, Esther; Menéndez, Manuel

doi:10.1016/0720-048x(92)90106-j

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…It is worth pointing out that, in several reports, the authors commented on the observation that, although KS osseous lesions were detected with MRI and CT scans, the same osseous lesions were not detected on plain x-rays despite their osteolytic character. 21,25,36 MRI also proved to be more accurate than other imaging modalities (ie, x-ray and CT) for assessing soft tissue extension of KS lesions 16 and spongy bone involvement 12 for detecting diffuse bone marrow involvement. 26 Ultrasound findings were reported in 2 patients, including 1 patient with classic KS involving the humerus who had associated enlargement of the scapulohumeral joint space and 1 AIDS patient who had KS infiltration of the gastrocnemius muscle.…”

Section: Radiology Findingsmentioning

confidence: 99%

Kaposi sarcoma of the musculoskeletal system

Caponetti

Dezube

Restrepo

et al. 2007

Cancer

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Kaposi sarcoma (KS) of bone and skeletal muscle is unusual. In this report, the authors review 66 published patients with KS who had involvement of the musculoskeletal system reported from 1925 to 2006. In only 3 patients was acquired immunodeficiency syndrome (AIDS)-related KS identified within skeletal muscle.Osseous KS lesions were more frequent and occurred with African, classic, and AIDS-related KS and occurred rarely in transplantation-associated KS. Patients seldom were asymptomatic. They usually had bone pain with limited mobility or infrequently developed serious sequelae like spinal cord compression. Locally aggressive African and classic KS lesions typically involved the peripheral skeleton; whereas, in patients with AIDS, the axial (vertebrae, ribs, sternum, and pelvis) and/or maxillofacial bones more commonly were involved. Almost all patients had concomitant nonosseous KS lesions. Joint involvement was exceptional, and pathologic fractures were not observed. Computed tomography scans and magnetic resonance images were better at detecting osseous KS lesions, which frequently went undetected on plain x-ray films or bone scans. Pathologic diagnosis was important to exclude similar lesions like bacillary angiomatosis.Treatment options, including surgery and, in more recent patients, radiation and/or chemotherapy, had limited success.

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Section: Radiology Findingsmentioning

confidence: 99%

Kaposi sarcoma of the musculoskeletal system

Caponetti

Dezube

Restrepo

et al. 2007

Cancer

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“…Bone involvement has been reported in some cases of classical KS [2, 3, 4, 5, 6]. The frequency of bone involvement appears to be variable since no case was reported in the series of 67 classical KS of Friedman-Birnbaum et al [1], while 3 cases were reported in the series of 66 cases of Stratigos et al [5].…”

Section: Discussionmentioning

confidence: 70%

“…Extracutaneous lesions are rare in classical KS [1]and bone involvement has rarely been reported [2, 3, 4, 5, 6]. However, bone involvement seems to be more frequent in African KS [7]and AIDS-related KS [8, 9, 10, 11, 12, 13, 14].…”

Section: Introductionmentioning

confidence: 99%

Bone Involvement in a Case of Kaposi Sarcoma

Ritz-Quillac¹,

Machet²,

Machet³

et al. 1999

Dermatology

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Background: Extracutaneous involvement is rare in the classical form of Kaposi sarcoma (KS). Observation: We report a case of bone involvement revealed by bone pain. Magnetic resonance (MR) images demonstrated the local invasion of bone from cutaneous lesions. Bone biopsy confirmed bone involvement. The patient was treated with vindesine. Bone pain progressively disappeared. Conclusion: Bone involvement has rarely been reported in classical KS though 4.5% of the patients were affected when it was systematically sought. Treatment of symptomatic lesions requires radiotherapy or chemotherapy.

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