Kaposi's varicelliform eruption due to herpes simplex in Darier's disease

Parslew, Richard; Verbov, Julian

doi:10.1111/j.1365-2230.1994.tb02703.x

Cited by 18 publications

(11 citation statements)

References 9 publications

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“…Darier’s disease is an autosomal dominant disorder and the gene has been mapped to chromosome 12q23–q24.1 [94, 95]. The warty, brown papules and plaques develop on the trunk but very often manifest themselves on the neck [96]. Often flexural involvement is observed which may produce malodorous papillomatous masses.…”

Section: Disorders Of Cornification and Related Disordersmentioning

confidence: 99%

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Itin

Lautenschläger

1998

Dermatology

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Reticulate pigmentation of the neck is a common finding in numerous genodermatoses and acquired diseases. As the neck is readily accessible to medical inspection, it may serve as a diagnostic window for various dermatoses. Several entities out of the spectrum of ectodermal dysplasia present with reticulate or mottled pigmentation on the upper trunk and neck. The most impressive genodermatoses with punctate and reticulate pigmentation affecting the neck are the Naegeli-Franceschetti-Jadassohn syndrome, dermatopathia pigmentosa reticularis and dyskeratosis congenita. Reticulate pigmented anomaly of the flexures and lentiginosis, disorders of cornification and related entities are further genodermatoses which may involve the neck. In our review we have integrated inherited dermatoses which do not obligatorily affect the neck but have been well documented to do so. Our work should give the clinician a checklist on genodermatoses which may produce reticulate and mottled pigmentation on the neck.

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Section: Disorders Of Cornification and Related Disordersmentioning

confidence: 99%

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Itin

Lautenschläger

1998

Dermatology

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“…17 In cases of Darier's disease and Hailey Hailey disease, KVE has been associated with oral retinoid therapy. [28][29][30] This association may be coincidental, not causative; nonetheless, KVE needs to be considered in individuals with erythroderma and in those treated with immunosuppressant agents and oral retinoids. Two of our patients were also receiving daily whirlpool therapy for treatment of their erythroderma.…”

Section: Discussionmentioning

confidence: 99%

Psoriasis herpeticum: Three cases of Kaposi's varicelliform eruption in psoriasis

Santmyire-Rosenberger

Nigra

2005

Journal of the American Academy of Dermatology

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“…When herpes simplex virus affects these patients, they tend to develop a widespread punched-out lesion, rather than a limited localized lesion observed in most nonatopic individuals [103]. This widespread herpes infection, termed 'eczema herpeticum' (or Kaposi's varicelliform eruption), cannot be explained by a potential immunological defect in atopic dermatitis alone, since the clinical phenotype of eczema herpeticum can also be observed to occur in patients who have other heritable skin diseases due to epidermal defect, termed Darier's disease and Hailey-Hailey disease (familial benign pemphigus), which are not known to have immunological defect [104][105][106][107]. Furthermore, eczema herpeticum has been reported to occur after dermabrasion, a surgical procedure that physically causes skin barrier defect, or in healing burned skin where skin barrier is compromised [108,109].…”

Section: Data From Human Patient Studiesmentioning

confidence: 95%

Atopic Dermatitis in 2008

Chan¹

2008

Current Directions in Autoimmunity

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Atopic dermatitis (also termed atopic eczema and infantile eczema), a chronic, itchy, inflammatory skin disease that sets on at infancy or early childhood, is observed with increasing prevalence around the world, particularly in developed nations. Although sufficient evidences are not yet available to define it as a classical autoimmune disease, autoantigens have been identified. Investigations of atopic dermatitis in human patients and animal models suggest that this disease is initiated, maintained and perpetuated by the actions of cytokines, chemokines, T cells, antigen-presenting cells and other inflammatory cells; there is also evidence of skin barrier defect and angiogenesis. Recent identification of mutations of the epidermal barrier protein filaggrin (encoded by FLG), present in about 9% of people of European origin, with 70% of individuals homozygous or compound heterozygous for FLG null alleles developing atopic dermatitis, provides a strong link between a defect of the epidermal barrier that allows easy penetration of pathogen/allergen through the skin and a systemic hyperactive immune response to the penetrated pathogen/allergen. The newly introduced concept of 'intrinsic' and 'extrinsic' atopic dermatitis has fueled the debate among academic dermatologists as to how 'atopic' atopic dermatitis should be defined. Some recent advancements on the management options for atopic dermatitis are also discussed.

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Kaposi's varicelliform eruption due to herpes simplex in Darier's disease

Cited by 18 publications

References 9 publications

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Genodermatosis with Reticulate, Patchy and Mottled Pigmentation of the Neck – A Clue to Rare Dermatologic Disorders

Psoriasis herpeticum: Three cases of Kaposi's varicelliform eruption in psoriasis

Atopic Dermatitis in 2008

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